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Effect of a high-monounsaturated fat diet enriched with avocado in NIDDM patients.
Diabetes Care. 1994 Apr; 17(4):311-5.DC

Abstract

OBJECTIVE

To assess the effects of two controlled diets, one rich in oleic acid obtained from avocado and olive oil and the other rich in complex carbohydrates, on fasting and postprandial serum lipids and glycemic control in 12 women with NIDDM.

RESEARCH DESIGN AND METHODS

A randomized crossover study was designed. During a 4-week baseline period, all patients received the isocaloric diets recommended by the American Diabetes Association. After this period the patients were randomly assigned to receive the two study diets alternatively during two 4-week periods. One diet was high in monounsaturated fatty acids (HMUFA) and the other was high in complex carbohydrates (high-CHO). There also was a 4-week washout period in between the two 4-week periods during which the patients followed the American Diabetes Association's isocaloric diet. Blood samples were obtained before and after each dietary period.

RESULTS

Both diets had a minor hypocholesterolemic effect with no major changes in high-density lipoprotein cholesterol. The HMUFA diet was associated with a greater decrement in plasma triglycerides (20 vs. 7% in the high-CHO diet). Glycemic control was similar with both diets.

CONCLUSIONS

Partial replacement of complex digestible carbohydrates with monounsaturated fatty acids (avocado as one of its main sources) in the diet of patients with non-insulin-dependent diabetes mellitus improves the lipid profile favorably, maintains an adequate glycemic control, and offers a good management alternative.

Authors+Show Affiliations

Department of Endocrinology, National Institute of Cardiology Ignacio Chávez, Mexico City, Mexico.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

8026287

Citation

Lerman-Garber, I, et al. "Effect of a High-monounsaturated Fat Diet Enriched With Avocado in NIDDM Patients." Diabetes Care, vol. 17, no. 4, 1994, pp. 311-5.
Lerman-Garber I, Ichazo-Cerro S, Zamora-González J, et al. Effect of a high-monounsaturated fat diet enriched with avocado in NIDDM patients. Diabetes Care. 1994;17(4):311-5.
Lerman-Garber, I., Ichazo-Cerro, S., Zamora-González, J., Cardoso-Saldaña, G., & Posadas-Romero, C. (1994). Effect of a high-monounsaturated fat diet enriched with avocado in NIDDM patients. Diabetes Care, 17(4), 311-5.
Lerman-Garber I, et al. Effect of a High-monounsaturated Fat Diet Enriched With Avocado in NIDDM Patients. Diabetes Care. 1994;17(4):311-5. PubMed PMID: 8026287.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of a high-monounsaturated fat diet enriched with avocado in NIDDM patients. AU - Lerman-Garber,I, AU - Ichazo-Cerro,S, AU - Zamora-González,J, AU - Cardoso-Saldaña,G, AU - Posadas-Romero,C, PY - 1994/4/1/pubmed PY - 1994/4/1/medline PY - 1994/4/1/entrez SP - 311 EP - 5 JF - Diabetes care JO - Diabetes Care VL - 17 IS - 4 N2 - OBJECTIVE: To assess the effects of two controlled diets, one rich in oleic acid obtained from avocado and olive oil and the other rich in complex carbohydrates, on fasting and postprandial serum lipids and glycemic control in 12 women with NIDDM. RESEARCH DESIGN AND METHODS: A randomized crossover study was designed. During a 4-week baseline period, all patients received the isocaloric diets recommended by the American Diabetes Association. After this period the patients were randomly assigned to receive the two study diets alternatively during two 4-week periods. One diet was high in monounsaturated fatty acids (HMUFA) and the other was high in complex carbohydrates (high-CHO). There also was a 4-week washout period in between the two 4-week periods during which the patients followed the American Diabetes Association's isocaloric diet. Blood samples were obtained before and after each dietary period. RESULTS: Both diets had a minor hypocholesterolemic effect with no major changes in high-density lipoprotein cholesterol. The HMUFA diet was associated with a greater decrement in plasma triglycerides (20 vs. 7% in the high-CHO diet). Glycemic control was similar with both diets. CONCLUSIONS: Partial replacement of complex digestible carbohydrates with monounsaturated fatty acids (avocado as one of its main sources) in the diet of patients with non-insulin-dependent diabetes mellitus improves the lipid profile favorably, maintains an adequate glycemic control, and offers a good management alternative. SN - 0149-5992 UR - https://www.unboundmedicine.com/medline/citation/8026287/Effect_of_a_high_monounsaturated_fat_diet_enriched_with_avocado_in_NIDDM_patients_ L2 - https://medlineplus.gov/diabeticdiet.html DB - PRIME DP - Unbound Medicine ER -