Tags

Type your tag names separated by a space and hit enter

Divided attention task performance and subjective effects following alcohol and placebo: differences between women with and without a family history of alcoholism.
Drug Alcohol Depend 1994; 35(2):95-105DA

Abstract

Women with (FHP) and without (FHN) family histories of alcoholism received either 0.56 g/kg alcohol or an isocaloric placebo in a repeated measures group design. Subjects performed a divided attention task and gave subjective ratings of 12 alcohol effects over a 3-h interval. After comparable doses of alcohol, 7 FHP and 10 FHN women had comparable ascending (blood alcohol levels) BALs. BALs peaked earlier for FHP women and then steadily declined. FHP women had a concomitant increase in visual search response times 30 min after alcohol. In contrast, scores on a simultaneously presented compensatory tracking task were virtually identical for the 7 FHP and 10 FHN women after alcohol and for the 8 FHP and 10 FHN women after placebo. After alcohol the FHP and FHN women had 7 out of 12 significantly different subjective ratings of alcohol responses. FHP women had lower subjective responses to alcohol and lower BALs, but their subjective responses were more strongly correlated with BALs. Our findings for women studied in a group design confirm the lower magnitude of subjective responses reported for pair-matched FHP men following comparable doses of alcohol in within-subjects and between-subjects designs in other laboratories.

Authors+Show Affiliations

Department of Psychiatry, McLean Hospital, Harvard Medical School, Belmont, MA 02178.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

8055741

Citation

Lex, B W., et al. "Divided Attention Task Performance and Subjective Effects Following Alcohol and Placebo: Differences Between Women With and Without a Family History of Alcoholism." Drug and Alcohol Dependence, vol. 35, no. 2, 1994, pp. 95-105.
Lex BW, Rhoades EM, Teoh SK, et al. Divided attention task performance and subjective effects following alcohol and placebo: differences between women with and without a family history of alcoholism. Drug Alcohol Depend. 1994;35(2):95-105.
Lex, B. W., Rhoades, E. M., Teoh, S. K., Mendelson, J. H., & Greenwald, N. E. (1994). Divided attention task performance and subjective effects following alcohol and placebo: differences between women with and without a family history of alcoholism. Drug and Alcohol Dependence, 35(2), pp. 95-105.
Lex BW, et al. Divided Attention Task Performance and Subjective Effects Following Alcohol and Placebo: Differences Between Women With and Without a Family History of Alcoholism. Drug Alcohol Depend. 1994;35(2):95-105. PubMed PMID: 8055741.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Divided attention task performance and subjective effects following alcohol and placebo: differences between women with and without a family history of alcoholism. AU - Lex,B W, AU - Rhoades,E M, AU - Teoh,S K, AU - Mendelson,J H, AU - Greenwald,N E, PY - 1994/4/1/pubmed PY - 1994/4/1/medline PY - 1994/4/1/entrez SP - 95 EP - 105 JF - Drug and alcohol dependence JO - Drug Alcohol Depend VL - 35 IS - 2 N2 - Women with (FHP) and without (FHN) family histories of alcoholism received either 0.56 g/kg alcohol or an isocaloric placebo in a repeated measures group design. Subjects performed a divided attention task and gave subjective ratings of 12 alcohol effects over a 3-h interval. After comparable doses of alcohol, 7 FHP and 10 FHN women had comparable ascending (blood alcohol levels) BALs. BALs peaked earlier for FHP women and then steadily declined. FHP women had a concomitant increase in visual search response times 30 min after alcohol. In contrast, scores on a simultaneously presented compensatory tracking task were virtually identical for the 7 FHP and 10 FHN women after alcohol and for the 8 FHP and 10 FHN women after placebo. After alcohol the FHP and FHN women had 7 out of 12 significantly different subjective ratings of alcohol responses. FHP women had lower subjective responses to alcohol and lower BALs, but their subjective responses were more strongly correlated with BALs. Our findings for women studied in a group design confirm the lower magnitude of subjective responses reported for pair-matched FHP men following comparable doses of alcohol in within-subjects and between-subjects designs in other laboratories. SN - 0376-8716 UR - https://www.unboundmedicine.com/medline/citation/8055741/Divided_attention_task_performance_and_subjective_effects_following_alcohol_and_placebo:_differences_between_women_with_and_without_a_family_history_of_alcoholism_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0376-8716(94)90116-3 DB - PRIME DP - Unbound Medicine ER -