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HIV serosurveillance in Papua New Guinea.
P N G Med J. 1993 Sep; 36(3):187-91.PN

Abstract

To determine human immunodeficiency virus-1 (HIV-1) prevalence in low- and high-risk populations in Papua New Guinea (PNG), anonymous unlinked serosurveillance was conducted in government-administered antenatal and sexually transmitted disease (STD) clinics at six sites beginning in June 1989. Although 3 of 1233 samples were HIV positive in a pilot study, none of 7948 samples was HIV positive during the first full year of serosurveillance (June 1989--May 1990). HIV-infected people are also identified in PNG through clinical diagnostic testing. Although underreporting is probably substantial, 45 HIV-infected people had been identified in PNG (population 3.6 million) through diagnostic testing between 1987 and the end of the first serosurveillance year (May 1990). In view of the steadily emerging clinical problem of acquired immune deficiency syndrome (AIDS) in PNG, the negative results of serosurveillance required explanation. Three possibilities are proposed: 1) the sample size chosen could fail to detect a case 5% (or more) of the time under the likely conditions of this survey; 2) the populations chosen for surveillance may not, yet, be those in which HIV is circulating at this early stage of the epidemic in PNG; and 3) laboratory error could account for some false negative results. The first two of these, alone or in combination, are most likely. Limited surveillance continued in PNG in 1991 and 1992. By June of 1992, 5 of an additional 6035 serosurveillance samples had tested positive. All 5 were among 2000 samples from a single site, the Port Moresby STD Clinic.(

ABSTRACT

TRUNCATED AT 250 WORDS)

Authors+Show Affiliations

World Health Organization, Department of Health, Port Moresby, Papua New Guinea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8059543

Citation

O'Leary, M J., et al. "HIV Serosurveillance in Papua New Guinea." Papua and New Guinea Medical Journal, vol. 36, no. 3, 1993, pp. 187-91.
O'Leary MJ, van der Meijden WI, Malau C, et al. HIV serosurveillance in Papua New Guinea. P N G Med J. 1993;36(3):187-91.
O'Leary, M. J., van der Meijden, W. I., Malau, C., Delamare, O., & Pyakalyia, T. (1993). HIV serosurveillance in Papua New Guinea. Papua and New Guinea Medical Journal, 36(3), 187-91.
O'Leary MJ, et al. HIV Serosurveillance in Papua New Guinea. P N G Med J. 1993;36(3):187-91. PubMed PMID: 8059543.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - HIV serosurveillance in Papua New Guinea. AU - O'Leary,M J, AU - van der Meijden,W I, AU - Malau,C, AU - Delamare,O, AU - Pyakalyia,T, PY - 1993/9/1/pubmed PY - 1993/9/1/medline PY - 1993/9/1/entrez KW - Developing Countries KW - Diseases KW - Error Sources KW - Evaluation KW - Examinations And Diagnoses KW - Hiv Infections KW - Hiv Serodiagnosis KW - Laboratory Examinations And Diagnoses KW - Laboratory Procedures KW - Measurement KW - Melanesia KW - Monitoring KW - Oceania KW - Papua New Guinea KW - Prevalence KW - Research Methodology KW - Viral Diseases SP - 187 EP - 91 JF - Papua and New Guinea medical journal JO - P N G Med J VL - 36 IS - 3 N2 - To determine human immunodeficiency virus-1 (HIV-1) prevalence in low- and high-risk populations in Papua New Guinea (PNG), anonymous unlinked serosurveillance was conducted in government-administered antenatal and sexually transmitted disease (STD) clinics at six sites beginning in June 1989. Although 3 of 1233 samples were HIV positive in a pilot study, none of 7948 samples was HIV positive during the first full year of serosurveillance (June 1989--May 1990). HIV-infected people are also identified in PNG through clinical diagnostic testing. Although underreporting is probably substantial, 45 HIV-infected people had been identified in PNG (population 3.6 million) through diagnostic testing between 1987 and the end of the first serosurveillance year (May 1990). In view of the steadily emerging clinical problem of acquired immune deficiency syndrome (AIDS) in PNG, the negative results of serosurveillance required explanation. Three possibilities are proposed: 1) the sample size chosen could fail to detect a case 5% (or more) of the time under the likely conditions of this survey; 2) the populations chosen for surveillance may not, yet, be those in which HIV is circulating at this early stage of the epidemic in PNG; and 3) laboratory error could account for some false negative results. The first two of these, alone or in combination, are most likely. Limited surveillance continued in PNG in 1991 and 1992. By June of 1992, 5 of an additional 6035 serosurveillance samples had tested positive. All 5 were among 2000 samples from a single site, the Port Moresby STD Clinic.(ABSTRACT TRUNCATED AT 250 WORDS) SN - 0031-1480 UR - https://www.unboundmedicine.com/medline/citation/8059543/HIV_serosurveillance_in_Papua_New_Guinea_ L2 - http://www.diseaseinfosearch.org/result/9735 DB - PRIME DP - Unbound Medicine ER -