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Cytokine system as potential target for antipsoriatic therapy.
Exp Dermatol 1994; 3(1):1-8ED

Abstract

Cytokines are produced by a variety of cells and have numerous of overlapping activities. There is increasing evidence that cytokines play a crucial role in the pathogenesis of psoriasis and of other dermatologic diseases. This review summarizes current knowledge as to how the altered cytokine network is involved in the accumulation of inflammatory cells in lesional skin, and how the cytokines are involved in epidermal hyperproliferation. The actions of the most important therapeutic compounds, such as corticosteroids, dithranol, cyclosporine, retinoids, vitamin D3 analogues and ultraviolet radiation, on the cytokine system are also discussed. Consideration is given as to how the effects on the production of cytokines and/or cytokine receptors contribute to their therapeutic action.

Authors+Show Affiliations

Department of Dermatology, Albert Szent-Györgyi Medical University, Szeged, Hungary.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

8061931

Citation

Kemény, L, et al. "Cytokine System as Potential Target for Antipsoriatic Therapy." Experimental Dermatology, vol. 3, no. 1, 1994, pp. 1-8.
Kemény L, Michel G, Dobozy A, et al. Cytokine system as potential target for antipsoriatic therapy. Exp Dermatol. 1994;3(1):1-8.
Kemény, L., Michel, G., Dobozy, A., & Ruzicka, T. (1994). Cytokine system as potential target for antipsoriatic therapy. Experimental Dermatology, 3(1), pp. 1-8.
Kemény L, et al. Cytokine System as Potential Target for Antipsoriatic Therapy. Exp Dermatol. 1994;3(1):1-8. PubMed PMID: 8061931.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Cytokine system as potential target for antipsoriatic therapy. AU - Kemény,L, AU - Michel,G, AU - Dobozy,A, AU - Ruzicka,T, PY - 1994/2/1/pubmed PY - 1994/2/1/medline PY - 1994/2/1/entrez SP - 1 EP - 8 JF - Experimental dermatology JO - Exp. Dermatol. VL - 3 IS - 1 N2 - Cytokines are produced by a variety of cells and have numerous of overlapping activities. There is increasing evidence that cytokines play a crucial role in the pathogenesis of psoriasis and of other dermatologic diseases. This review summarizes current knowledge as to how the altered cytokine network is involved in the accumulation of inflammatory cells in lesional skin, and how the cytokines are involved in epidermal hyperproliferation. The actions of the most important therapeutic compounds, such as corticosteroids, dithranol, cyclosporine, retinoids, vitamin D3 analogues and ultraviolet radiation, on the cytokine system are also discussed. Consideration is given as to how the effects on the production of cytokines and/or cytokine receptors contribute to their therapeutic action. SN - 0906-6705 UR - https://www.unboundmedicine.com/medline/citation/8061931/Cytokine_system_as_potential_target_for_antipsoriatic_therapy_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0906-6705&date=1994&volume=3&issue=1&spage=1 DB - PRIME DP - Unbound Medicine ER -