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Influence of Tołpa Peat Preparation on haemostasis in rats.
Acta Pol Pharm 1993; 50(6):507-11AP

Abstract

The influence of Tołpa Peat Preparation (TPP) on certain parameters of haemostasis was studied. The present results indicate that TPP (100, 200 and 300 mg/kg p.o.) had no influence on the bleeding time, clotting time, thrombin time, prothrombin time, kaolin-kephalin time, euglobulin lysis time, the concentration of fibrinogen, the platelet count and ADP-induced platelet aggregation. No changes in animals after long-term treatment with TPP (100 mg/kg for two weeks) were found either. In in vitro studies TPP given in concentrations 10(-5), 10(-4), 10(-3) and 10(-2) g/cm3 was used and certain changes of the studied parameters, probably caused by the presence of high salt content in this substance, were observed.

Authors+Show Affiliations

Department of Pharmacodynamics, School of Medicine, Białystok, Poland.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8067264

Citation

Buczko, W, et al. "Influence of Tołpa Peat Preparation On Haemostasis in Rats." Acta Poloniae Pharmaceutica, vol. 50, no. 6, 1993, pp. 507-11.
Buczko W, Malinowska B, Pietraszek MH, et al. Influence of Tołpa Peat Preparation on haemostasis in rats. Acta Pol Pharm. 1993;50(6):507-11.
Buczko, W., Malinowska, B., Pietraszek, M. H., Pawlak, D., & Chabielska, E. (1993). Influence of Tołpa Peat Preparation on haemostasis in rats. Acta Poloniae Pharmaceutica, 50(6), pp. 507-11.
Buczko W, et al. Influence of Tołpa Peat Preparation On Haemostasis in Rats. Acta Pol Pharm. 1993;50(6):507-11. PubMed PMID: 8067264.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Influence of Tołpa Peat Preparation on haemostasis in rats. AU - Buczko,W, AU - Malinowska,B, AU - Pietraszek,M H, AU - Pawlak,D, AU - Chabielska,E, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez SP - 507 EP - 11 JF - Acta poloniae pharmaceutica JO - Acta Pol Pharm VL - 50 IS - 6 N2 - The influence of Tołpa Peat Preparation (TPP) on certain parameters of haemostasis was studied. The present results indicate that TPP (100, 200 and 300 mg/kg p.o.) had no influence on the bleeding time, clotting time, thrombin time, prothrombin time, kaolin-kephalin time, euglobulin lysis time, the concentration of fibrinogen, the platelet count and ADP-induced platelet aggregation. No changes in animals after long-term treatment with TPP (100 mg/kg for two weeks) were found either. In in vitro studies TPP given in concentrations 10(-5), 10(-4), 10(-3) and 10(-2) g/cm3 was used and certain changes of the studied parameters, probably caused by the presence of high salt content in this substance, were observed. SN - 0001-6837 UR - https://www.unboundmedicine.com/medline/citation/8067264/Influence_of_Tołpa_Peat_Preparation_on_haemostasis_in_rats_ DB - PRIME DP - Unbound Medicine ER -