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Dynamic liver radionuclide scanning in the evaluation of liver failure and portal hypertension in cirrhotic patients.
J Nucl Biol Med. 1994 Mar; 38(1):1-5.JN

Abstract

Dynamic liver radionuclide scanning was performed in cirrhotic patients to correlate three parameters derived by this technique to the severity of liver function impairment and clinical-endoscopic signs of portal hypertension. We found a close association between the severity of liver failure (Child-Pugh criteria) and both the relative blood flow (p < 0.05) and the shape (shifting to the left) of the early flow curve (p < 0.01). A significant association between the presence of portal hypertension and shifting to the left of the flow curve was demonstrated in all cases in which tense ascites was associated with varices (p < 0.05). Finally, a statistically significant association (p < 0.05) was found between the degree of esophageal varices (Beppu's criteria) and the liver-to-spleen uptake ratio. These data suggest that dynamic isotope liver scanning could be an important tool in the diagnostic evaluation of liver function impairment and portal hypertension.

Authors+Show Affiliations

Division of Nuclear Medicine, Venice General Hospital, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8075170

Citation

Bonazza, A, et al. "Dynamic Liver Radionuclide Scanning in the Evaluation of Liver Failure and Portal Hypertension in Cirrhotic Patients." Journal of Nuclear Biology and Medicine (Turin, Italy : 1991), vol. 38, no. 1, 1994, pp. 1-5.
Bonazza A, Moro E, Alessandrini P, et al. Dynamic liver radionuclide scanning in the evaluation of liver failure and portal hypertension in cirrhotic patients. J Nucl Biol Med. 1994;38(1):1-5.
Bonazza, A., Moro, E., Alessandrini, P., Gravili, S., & Bittolo Bon, G. (1994). Dynamic liver radionuclide scanning in the evaluation of liver failure and portal hypertension in cirrhotic patients. Journal of Nuclear Biology and Medicine (Turin, Italy : 1991), 38(1), 1-5.
Bonazza A, et al. Dynamic Liver Radionuclide Scanning in the Evaluation of Liver Failure and Portal Hypertension in Cirrhotic Patients. J Nucl Biol Med. 1994;38(1):1-5. PubMed PMID: 8075170.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Dynamic liver radionuclide scanning in the evaluation of liver failure and portal hypertension in cirrhotic patients. AU - Bonazza,A, AU - Moro,E, AU - Alessandrini,P, AU - Gravili,S, AU - Bittolo Bon,G, PY - 1994/3/1/pubmed PY - 1994/3/1/medline PY - 1994/3/1/entrez SP - 1 EP - 5 JF - Journal of nuclear biology and medicine (Turin, Italy : 1991) JO - J Nucl Biol Med VL - 38 IS - 1 N2 - Dynamic liver radionuclide scanning was performed in cirrhotic patients to correlate three parameters derived by this technique to the severity of liver function impairment and clinical-endoscopic signs of portal hypertension. We found a close association between the severity of liver failure (Child-Pugh criteria) and both the relative blood flow (p < 0.05) and the shape (shifting to the left) of the early flow curve (p < 0.01). A significant association between the presence of portal hypertension and shifting to the left of the flow curve was demonstrated in all cases in which tense ascites was associated with varices (p < 0.05). Finally, a statistically significant association (p < 0.05) was found between the degree of esophageal varices (Beppu's criteria) and the liver-to-spleen uptake ratio. These data suggest that dynamic isotope liver scanning could be an important tool in the diagnostic evaluation of liver function impairment and portal hypertension. SN - 0368-3249 UR - https://www.unboundmedicine.com/medline/citation/8075170/Dynamic_liver_radionuclide_scanning_in_the_evaluation_of_liver_failure_and_portal_hypertension_in_cirrhotic_patients_ L2 - http://www.diseaseinfosearch.org/result/5881 DB - PRIME DP - Unbound Medicine ER -