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The effect of maternal ethanol intoxication on erythrocyte ghost fluidity in new-born rat pups.
Biochem Mol Biol Int. 1994 May; 33(1):1-8.BM

Abstract

We administered ethanol to pregnant rats and determined cholesterol, lipid phosphorus and fluorescence anisotropy of diphenylhexatriene (DPH) and of trimethylaminophenyl hexatriene (TMA-DPH) in erythrocyte ghosts of newborn pups and of their mothers. Cholesterol content was different in dams and pups and changed after treatment. Age, but not ethanol, affected lipid phosphorus. Either age (dams versus pups) or treatment affected the curves of DPH fluorescence anisotropy (r) versus temperature (T), but those of TMA-DPH did not change, indicating that only the inner core of the membrane was influenced. We conclude that adult and erythrocyte ghosts differed for the lipid composition, for the dependence of r on T (for DPH) and for the effects of ethanol dosing on these parameters.

Authors+Show Affiliations

Department of Biochemistry, Medical School, University of Perugia, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8081199

Citation

Arienti, G, et al. "The Effect of Maternal Ethanol Intoxication On Erythrocyte Ghost Fluidity in New-born Rat Pups." Biochemistry and Molecular Biology International, vol. 33, no. 1, 1994, pp. 1-8.
Arienti G, Battistoni F, Carlini E, et al. The effect of maternal ethanol intoxication on erythrocyte ghost fluidity in new-born rat pups. Biochem Mol Biol Int. 1994;33(1):1-8.
Arienti, G., Battistoni, F., Carlini, E., Di Renzo, G. C., Cosmi, E. V., & Reboldi, G. P. (1994). The effect of maternal ethanol intoxication on erythrocyte ghost fluidity in new-born rat pups. Biochemistry and Molecular Biology International, 33(1), 1-8.
Arienti G, et al. The Effect of Maternal Ethanol Intoxication On Erythrocyte Ghost Fluidity in New-born Rat Pups. Biochem Mol Biol Int. 1994;33(1):1-8. PubMed PMID: 8081199.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The effect of maternal ethanol intoxication on erythrocyte ghost fluidity in new-born rat pups. AU - Arienti,G, AU - Battistoni,F, AU - Carlini,E, AU - Di Renzo,G C, AU - Cosmi,E V, AU - Reboldi,G P, PY - 1994/5/1/pubmed PY - 1994/5/1/medline PY - 1994/5/1/entrez SP - 1 EP - 8 JF - Biochemistry and molecular biology international JO - Biochem Mol Biol Int VL - 33 IS - 1 N2 - We administered ethanol to pregnant rats and determined cholesterol, lipid phosphorus and fluorescence anisotropy of diphenylhexatriene (DPH) and of trimethylaminophenyl hexatriene (TMA-DPH) in erythrocyte ghosts of newborn pups and of their mothers. Cholesterol content was different in dams and pups and changed after treatment. Age, but not ethanol, affected lipid phosphorus. Either age (dams versus pups) or treatment affected the curves of DPH fluorescence anisotropy (r) versus temperature (T), but those of TMA-DPH did not change, indicating that only the inner core of the membrane was influenced. We conclude that adult and erythrocyte ghosts differed for the lipid composition, for the dependence of r on T (for DPH) and for the effects of ethanol dosing on these parameters. SN - 1039-9712 UR - https://www.unboundmedicine.com/medline/citation/8081199/The_effect_of_maternal_ethanol_intoxication_on_erythrocyte_ghost_fluidity_in_new_born_rat_pups_ L2 - https://medlineplus.gov/fetalalcoholspectrumdisorders.html DB - PRIME DP - Unbound Medicine ER -