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Stereotaxic large-core needle biopsy of 450 nonpalpable breast lesions with surgical correlation in lesions with cancer or atypical hyperplasia.
Radiology. 1994 Oct; 193(1):91-5.R

Abstract

PURPOSE

To determine whether histologic findings of cancer or atypical hyperplasia at large-core needle biopsy (LCNB) of nonpalpable breast lesions match histologic findings at excision.

MATERIALS AND METHODS

Stereotaxic LCNB was performed with an automated prone unit, biopsy gun, and 14-gauge cutting needles in 450 nonpalpable breast lesions. Lesions classified as carcinoma or atypical ductal hyperplasia (ADH) at histologic examination after LCNB were excised. A pathologist retrospectively compared core and excisional histologic findings.

RESULTS

Histologic comparison was performed in 116 of 135 carcinomas after LCNB. Histologic findings were concordant in 99 carcinomas. Partial discordance in 17 carcinomas led to an additional surgical procedure in one case. Histologic comparison was performed in 16 of 19 ADHs diagnosed with LCNB. Histologic findings were concordant in five and discordant in 11 ADHs.

CONCLUSION

LCNB findings of carcinoma are accurate and allow definitive therapeutic surgery, including mastectomy. LCNB findings of ADH are inaccurate, and excisional biopsy is necessary.

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Publisher Full Text

Authors+Show Affiliations

Jackman RJ
Department of Radiology, Palo Alto Medical Clinic, CA 94301.
Nowels KW
No affiliation info available
Shepard MJ
No affiliation info available
Finkelstein SI
No affiliation info available
Marzoni FA
No affiliation info available

MeSH

Biopsy, NeedleBreastBreast NeoplasmsCarcinoma in SituCarcinoma, Ductal, BreastCarcinoma, LobularFemaleHumansHyperplasiaRetrospective StudiesStereotaxic Techniques

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

8090927

Citation

Jackman, R J., et al. "Stereotaxic Large-core Needle Biopsy of 450 Nonpalpable Breast Lesions With Surgical Correlation in Lesions With Cancer or Atypical Hyperplasia." Radiology, vol. 193, no. 1, 1994, pp. 91-5.
Jackman RJ, Nowels KW, Shepard MJ, et al. Stereotaxic large-core needle biopsy of 450 nonpalpable breast lesions with surgical correlation in lesions with cancer or atypical hyperplasia. Radiology. 1994;193(1):91-5.
Jackman, R. J., Nowels, K. W., Shepard, M. J., Finkelstein, S. I., & Marzoni, F. A. (1994). Stereotaxic large-core needle biopsy of 450 nonpalpable breast lesions with surgical correlation in lesions with cancer or atypical hyperplasia. Radiology, 193(1), 91-5.
Jackman RJ, et al. Stereotaxic Large-core Needle Biopsy of 450 Nonpalpable Breast Lesions With Surgical Correlation in Lesions With Cancer or Atypical Hyperplasia. Radiology. 1994;193(1):91-5. PubMed PMID: 8090927.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Stereotaxic large-core needle biopsy of 450 nonpalpable breast lesions with surgical correlation in lesions with cancer or atypical hyperplasia. AU - Jackman,R J, AU - Nowels,K W, AU - Shepard,M J, AU - Finkelstein,S I, AU - Marzoni,F A,Jr PY - 1994/10/1/pubmed PY - 2001/3/28/medline PY - 1994/10/1/entrez SP - 91 EP - 5 JF - Radiology JO - Radiology VL - 193 IS - 1 N2 - PURPOSE: To determine whether histologic findings of cancer or atypical hyperplasia at large-core needle biopsy (LCNB) of nonpalpable breast lesions match histologic findings at excision. MATERIALS AND METHODS: Stereotaxic LCNB was performed with an automated prone unit, biopsy gun, and 14-gauge cutting needles in 450 nonpalpable breast lesions. Lesions classified as carcinoma or atypical ductal hyperplasia (ADH) at histologic examination after LCNB were excised. A pathologist retrospectively compared core and excisional histologic findings. RESULTS: Histologic comparison was performed in 116 of 135 carcinomas after LCNB. Histologic findings were concordant in 99 carcinomas. Partial discordance in 17 carcinomas led to an additional surgical procedure in one case. Histologic comparison was performed in 16 of 19 ADHs diagnosed with LCNB. Histologic findings were concordant in five and discordant in 11 ADHs. CONCLUSION: LCNB findings of carcinoma are accurate and allow definitive therapeutic surgery, including mastectomy. LCNB findings of ADH are inaccurate, and excisional biopsy is necessary. SN - 0033-8419 UR - https://www.unboundmedicine.com/medline/citation/8090927/Stereotaxic_large_core_needle_biopsy_of_450_nonpalpable_breast_lesions_with_surgical_correlation_in_lesions_with_cancer_or_atypical_hyperplasia_ L2 - https://pubs.rsna.org/doi/10.1148/radiology.193.1.8090927?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -