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Acute exercise- and drug-induced potassium shifts during pregnancy.
Ann Chir Gynaecol Suppl. 1994; 208:88-90.AC

Abstract

The exercise- and drug-induced potassium shifts in pregnant women was studied. Six healthy nonpregnant women, six healthy pregnant women and four hypertensive, pregnant women on labetalol performed a bicycle exercise test. Blood samples for plasma potassium concentrations were drawn before, during and after the exercise. The exercise-induced plasma potassium increase was 0.9 +/- 0.2 mmol/l in healthy control women and 0.8 +/- 0.1 mmol/l in healthy pregnant women. In hypertensive pregnant women on labetalol the increase was 0.3 +/- 0.3 mmol/l (P < 0.01). There was a negative correlation (r = 0.941, P = 0.05) between the plasma potassium and labetalol concentration. Our results suggest that the potassium exchange during normal pregnancy is not changed. Labetalol reduced the exercise-induced plasma potassium increase which contrasts to other beta-blocking agents which usually augment the plasma potassium increase caused by exercise.

Authors+Show Affiliations

Department of Medicine, Clinical Pharmacology, and Obstetrics and Gynecology, Turku University Central Hospital, Finland.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8092783

Citation

Kantola, I, et al. "Acute Exercise- and Drug-induced Potassium Shifts During Pregnancy." Annales Chirurgiae Et Gynaecologiae. Supplementum, vol. 208, 1994, pp. 88-90.
Kantola I, Kaila T, Erkkola R. Acute exercise- and drug-induced potassium shifts during pregnancy. Ann Chir Gynaecol Suppl. 1994;208:88-90.
Kantola, I., Kaila, T., & Erkkola, R. (1994). Acute exercise- and drug-induced potassium shifts during pregnancy. Annales Chirurgiae Et Gynaecologiae. Supplementum, 208, 88-90.
Kantola I, Kaila T, Erkkola R. Acute Exercise- and Drug-induced Potassium Shifts During Pregnancy. Ann Chir Gynaecol Suppl. 1994;208:88-90. PubMed PMID: 8092783.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acute exercise- and drug-induced potassium shifts during pregnancy. AU - Kantola,I, AU - Kaila,T, AU - Erkkola,R, PY - 1994/1/1/pubmed PY - 1994/1/1/medline PY - 1994/1/1/entrez SP - 88 EP - 90 JF - Annales chirurgiae et gynaecologiae. Supplementum JO - Ann Chir Gynaecol Suppl VL - 208 N2 - The exercise- and drug-induced potassium shifts in pregnant women was studied. Six healthy nonpregnant women, six healthy pregnant women and four hypertensive, pregnant women on labetalol performed a bicycle exercise test. Blood samples for plasma potassium concentrations were drawn before, during and after the exercise. The exercise-induced plasma potassium increase was 0.9 +/- 0.2 mmol/l in healthy control women and 0.8 +/- 0.1 mmol/l in healthy pregnant women. In hypertensive pregnant women on labetalol the increase was 0.3 +/- 0.3 mmol/l (P < 0.01). There was a negative correlation (r = 0.941, P = 0.05) between the plasma potassium and labetalol concentration. Our results suggest that the potassium exchange during normal pregnancy is not changed. Labetalol reduced the exercise-induced plasma potassium increase which contrasts to other beta-blocking agents which usually augment the plasma potassium increase caused by exercise. SN - 0355-9874 UR - https://www.unboundmedicine.com/medline/citation/8092783/Acute_exercise__and_drug_induced_potassium_shifts_during_pregnancy_ L2 - http://www.diseaseinfosearch.org/result/5922 DB - PRIME DP - Unbound Medicine ER -
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