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Combined treatment strategies in psychiatry.
J Clin Psychiatry 1993; 54 Suppl:42-9; discussion 55-6JC

Abstract

Combination drug regimens are commonly employed in the treatment of psychiatric disorders. Virtually all classes of psychotropic medications have been used in combination and for a variety of indications. Some drug combinations are thought to be synergistic, and others are used to treat different target symptoms. Combination therapies are used as the primary treatment for certain disorders (antipsychotic-antidepressant combinations in psychotic depression); as adjunctive treatment for patients refractory to initial drug therapy (lithium augmentation in refractory depression); and as treatment for the emergence of a secondary disorder (depression in a schizophrenic patient). Since combination treatment may increase the risk of adverse reactions through either pharmacodynamic or pharmacokinetic interactions, knowledge of these interactions and their possible adverse effects is crucial.

Authors+Show Affiliations

Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06504.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

8104933

Citation

Nelson, J C.. "Combined Treatment Strategies in Psychiatry." The Journal of Clinical Psychiatry, vol. 54 Suppl, 1993, pp. 42-9; discussion 55-6.
Nelson JC. Combined treatment strategies in psychiatry. J Clin Psychiatry. 1993;54 Suppl:42-9; discussion 55-6.
Nelson, J. C. (1993). Combined treatment strategies in psychiatry. The Journal of Clinical Psychiatry, 54 Suppl, pp. 42-9; discussion 55-6.
Nelson JC. Combined Treatment Strategies in Psychiatry. J Clin Psychiatry. 1993;54 Suppl:42-9; discussion 55-6. PubMed PMID: 8104933.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Combined treatment strategies in psychiatry. A1 - Nelson,J C, PY - 1993/9/1/pubmed PY - 1993/9/1/medline PY - 1993/9/1/entrez SP - 42-9; discussion 55-6 JF - The Journal of clinical psychiatry JO - J Clin Psychiatry VL - 54 Suppl N2 - Combination drug regimens are commonly employed in the treatment of psychiatric disorders. Virtually all classes of psychotropic medications have been used in combination and for a variety of indications. Some drug combinations are thought to be synergistic, and others are used to treat different target symptoms. Combination therapies are used as the primary treatment for certain disorders (antipsychotic-antidepressant combinations in psychotic depression); as adjunctive treatment for patients refractory to initial drug therapy (lithium augmentation in refractory depression); and as treatment for the emergence of a secondary disorder (depression in a schizophrenic patient). Since combination treatment may increase the risk of adverse reactions through either pharmacodynamic or pharmacokinetic interactions, knowledge of these interactions and their possible adverse effects is crucial. SN - 0160-6689 UR - https://www.unboundmedicine.com/medline/citation/8104933/Combined_treatment_strategies_in_psychiatry_ L2 - https://medlineplus.gov/childmentalhealth.html DB - PRIME DP - Unbound Medicine ER -