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Trabeculectomy is associated with retrobulbar hemodynamic changes. A color Doppler analysis.
Ophthalmology. 1994 Feb; 101(2):340-51.O

Abstract

PURPOSE

To determine whether color Doppler hemodynamic changes occur in the retrobulbar circulation after trabeculectomy.

METHODS

The authors prospectively enrolled 20 patients undergoing trabeculectomy and performed color Doppler imaging of both eyes before surgery and then at approximately 2-, 5-, and 14-week intervals after surgery. The systolic maximum velocity, mean velocity, end-diastolic velocity, and vascular resistance (resistance index) of the central retinal artery, nasal and temporal short posterior ciliary arteries, and ophthalmic arteries were determined. Statistical comparison of the preoperative and postoperative measures were performed on both the operative and nonoperative eye using the paired Student's t test.

RESULTS

A statistically significant increase was observed in the mean and end-diastolic velocity and a significant decrease in the vascular resistance of the central retinal artery and both short posterior ciliary arteries at nearly all postoperative intervals (25 of 27 preoperative and postoperative comparisons; P < 0.05) The ophthalmic artery, while showing an increased velocity at all intervals, only attained a statistically significant increase in one of three postoperative intervals for mean velocity and two of three intervals for end-diastolic velocity (P < 0.05). There were no notable changes in resistance. The nonoperative eye did not show a statistically significant change in velocity or in resistance in the central retinal artery or either nasal or temporal short posterior ciliary artery at any interval (0 of 27 preoperative and postoperative comparisons for mean velocity, end-diastolic velocity, and resistance index.)

CONCLUSION

Sustained increases in mean velocity and end-diastolic velocity and decreases in resistance index were observed in the central retinal artery and the short posterior arteries with clinically attainable reductions in intraocular pressure after trabeculectomy in patients with chronic glaucoma. These findings are consistent with, but not diagnostic of, increased blood flow through these vessels.

Authors+Show Affiliations

Neuro-Ophthalmology Service, Wills Eye Hospital, Philadelphia 19107.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8115155

Citation

Trible, J R., et al. "Trabeculectomy Is Associated With Retrobulbar Hemodynamic Changes. a Color Doppler Analysis." Ophthalmology, vol. 101, no. 2, 1994, pp. 340-51.
Trible JR, Sergott RC, Spaeth GL, et al. Trabeculectomy is associated with retrobulbar hemodynamic changes. A color Doppler analysis. Ophthalmology. 1994;101(2):340-51.
Trible, J. R., Sergott, R. C., Spaeth, G. L., Wilson, R. P., Katz, L. J., Moster, M. R., & Schmidt, C. M. (1994). Trabeculectomy is associated with retrobulbar hemodynamic changes. A color Doppler analysis. Ophthalmology, 101(2), 340-51.
Trible JR, et al. Trabeculectomy Is Associated With Retrobulbar Hemodynamic Changes. a Color Doppler Analysis. Ophthalmology. 1994;101(2):340-51. PubMed PMID: 8115155.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Trabeculectomy is associated with retrobulbar hemodynamic changes. A color Doppler analysis. AU - Trible,J R, AU - Sergott,R C, AU - Spaeth,G L, AU - Wilson,R P, AU - Katz,L J, AU - Moster,M R, AU - Schmidt,C M, PY - 1994/2/1/pubmed PY - 1994/2/1/medline PY - 1994/2/1/entrez SP - 340 EP - 51 JF - Ophthalmology JO - Ophthalmology VL - 101 IS - 2 N2 - PURPOSE: To determine whether color Doppler hemodynamic changes occur in the retrobulbar circulation after trabeculectomy. METHODS: The authors prospectively enrolled 20 patients undergoing trabeculectomy and performed color Doppler imaging of both eyes before surgery and then at approximately 2-, 5-, and 14-week intervals after surgery. The systolic maximum velocity, mean velocity, end-diastolic velocity, and vascular resistance (resistance index) of the central retinal artery, nasal and temporal short posterior ciliary arteries, and ophthalmic arteries were determined. Statistical comparison of the preoperative and postoperative measures were performed on both the operative and nonoperative eye using the paired Student's t test. RESULTS: A statistically significant increase was observed in the mean and end-diastolic velocity and a significant decrease in the vascular resistance of the central retinal artery and both short posterior ciliary arteries at nearly all postoperative intervals (25 of 27 preoperative and postoperative comparisons; P < 0.05) The ophthalmic artery, while showing an increased velocity at all intervals, only attained a statistically significant increase in one of three postoperative intervals for mean velocity and two of three intervals for end-diastolic velocity (P < 0.05). There were no notable changes in resistance. The nonoperative eye did not show a statistically significant change in velocity or in resistance in the central retinal artery or either nasal or temporal short posterior ciliary artery at any interval (0 of 27 preoperative and postoperative comparisons for mean velocity, end-diastolic velocity, and resistance index.) CONCLUSION: Sustained increases in mean velocity and end-diastolic velocity and decreases in resistance index were observed in the central retinal artery and the short posterior arteries with clinically attainable reductions in intraocular pressure after trabeculectomy in patients with chronic glaucoma. These findings are consistent with, but not diagnostic of, increased blood flow through these vessels. SN - 0161-6420 UR - https://www.unboundmedicine.com/medline/citation/8115155/Trabeculectomy_is_associated_with_retrobulbar_hemodynamic_changes__A_color_Doppler_analysis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0161-6420(94)31330-3 DB - PRIME DP - Unbound Medicine ER -