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Carcinoma in situ of the penis.
J Urol. 1994 Apr; 151(4):829-33.JU

Abstract

Bowen's disease, erythroplasia of Queyrat and bowenoid papulosis are uncommon disorders of the anogenital skin that may be confused with a variety of other lesions. While all appear histologically as carcinoma in situ and are strongly associated with human papillomavirus infection, only Bowen's disease and erythroplasia of Queyrat have been demonstrated to lead to the development of invasive squamous cell carcinoma. In contrast, bowenoid papulosis has a completely benign course with no present evidence suggesting the potential for malignant degeneration. The standard treatment for all 3 lesions in surgical excision, although use of the carbon dioxide or neodymium:YAG laser appears to be effective at obtaining local control of disease while achieving an excellent cosmetic result. Alternative treatments with micrographic surgery, topical 5-fluorouracil or radiotherapy have a more limited role. It is important to remember that adequate biopsies are always necessary to ensure a complete and accurate diagnosis, and allow for proper treatment and followup, as well as appropriate counseling of sexual partners.

Authors+Show Affiliations

Department of Surgery, University of Chicago Pritzker School of Medicine, Illinois.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

8126803

Citation

Gerber, G S.. "Carcinoma in Situ of the Penis." The Journal of Urology, vol. 151, no. 4, 1994, pp. 829-33.
Gerber GS. Carcinoma in situ of the penis. J Urol. 1994;151(4):829-33.
Gerber, G. S. (1994). Carcinoma in situ of the penis. The Journal of Urology, 151(4), 829-33.
Gerber GS. Carcinoma in Situ of the Penis. J Urol. 1994;151(4):829-33. PubMed PMID: 8126803.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Carcinoma in situ of the penis. A1 - Gerber,G S, PY - 1994/4/1/pubmed PY - 1994/4/1/medline PY - 1994/4/1/entrez SP - 829 EP - 33 JF - The Journal of urology JO - J Urol VL - 151 IS - 4 N2 - Bowen's disease, erythroplasia of Queyrat and bowenoid papulosis are uncommon disorders of the anogenital skin that may be confused with a variety of other lesions. While all appear histologically as carcinoma in situ and are strongly associated with human papillomavirus infection, only Bowen's disease and erythroplasia of Queyrat have been demonstrated to lead to the development of invasive squamous cell carcinoma. In contrast, bowenoid papulosis has a completely benign course with no present evidence suggesting the potential for malignant degeneration. The standard treatment for all 3 lesions in surgical excision, although use of the carbon dioxide or neodymium:YAG laser appears to be effective at obtaining local control of disease while achieving an excellent cosmetic result. Alternative treatments with micrographic surgery, topical 5-fluorouracil or radiotherapy have a more limited role. It is important to remember that adequate biopsies are always necessary to ensure a complete and accurate diagnosis, and allow for proper treatment and followup, as well as appropriate counseling of sexual partners. SN - 0022-5347 UR - https://www.unboundmedicine.com/medline/citation/8126803/Carcinoma_in_situ_of_the_penis_ L2 - https://www.jurology.com/doi/10.1016/s0022-5347(17)35099-1?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -