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Fluconazole-resistant Cryptococcus neoformans var gattii in an AIDS patient.
Acta Clin Belg. 1993; 48(6):405-9.AC

Abstract

We describe a case of meningitis due to Cryptococcus neoformans var gattii in an AIDS patient. The reasons for the observed predominance of C. neoformans var neoformans infections in AIDS patients living in areas endemic for the gattii variety are not understood thus far. Treatment with fluconazole resulted in poor clinical and mycological response. In vitro sensitivity testing of the fungus revealed high minimal inhibitory concentrations, suggesting fluconazole resistance. Treatment with amphotericin B was successful.

Authors+Show Affiliations

Peetermans W
Department of Internal Medicine, Universitaire Ziekenhuizen, K.U. Leuven, Belgium.
Bobbaers H
No affiliation info available
Verhaegen J
No affiliation info available
Vandepitte J
No affiliation info available

MeSH

AIDS-Related Opportunistic InfectionsAdultCryptococcus neoformansDrug Resistance, MicrobialFemaleFluconazoleHumansMeningitis, Cryptococcal

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

8128821

Citation

Peetermans, W, et al. "Fluconazole-resistant Cryptococcus Neoformans Var Gattii in an AIDS Patient." Acta Clinica Belgica, vol. 48, no. 6, 1993, pp. 405-9.
Peetermans W, Bobbaers H, Verhaegen J, et al. Fluconazole-resistant Cryptococcus neoformans var gattii in an AIDS patient. Acta Clin Belg. 1993;48(6):405-9.
Peetermans, W., Bobbaers, H., Verhaegen, J., & Vandepitte, J. (1993). Fluconazole-resistant Cryptococcus neoformans var gattii in an AIDS patient. Acta Clinica Belgica, 48(6), 405-9.
Peetermans W, et al. Fluconazole-resistant Cryptococcus Neoformans Var Gattii in an AIDS Patient. Acta Clin Belg. 1993;48(6):405-9. PubMed PMID: 8128821.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fluconazole-resistant Cryptococcus neoformans var gattii in an AIDS patient. AU - Peetermans,W, AU - Bobbaers,H, AU - Verhaegen,J, AU - Vandepitte,J, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez SP - 405 EP - 9 JF - Acta clinica Belgica JO - Acta Clin Belg VL - 48 IS - 6 N2 - We describe a case of meningitis due to Cryptococcus neoformans var gattii in an AIDS patient. The reasons for the observed predominance of C. neoformans var neoformans infections in AIDS patients living in areas endemic for the gattii variety are not understood thus far. Treatment with fluconazole resulted in poor clinical and mycological response. In vitro sensitivity testing of the fungus revealed high minimal inhibitory concentrations, suggesting fluconazole resistance. Treatment with amphotericin B was successful. SN - 1784-3286 UR - https://www.unboundmedicine.com/medline/citation/8128821/Fluconazole_resistant_Cryptococcus_neoformans_var_gattii_in_an_AIDS_patient_ L2 - http://www.diseaseinfosearch.org/result/279 DB - PRIME DP - Unbound Medicine ER -