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[Comparative evaluation of diabetic cardiac autonomic neuropathy by spectrum analysis and Ewing's tests].
Arch Mal Coeur Vaiss. 1993 Aug; 86(8):1143-8.AM

Abstract

METHODS

62 diabetic patients of both sex (age: 46 +/- 16 yr, BMI: 26.1 +/- 4 kg/m2, casual blood pressure: 134 +/- 17/81 +/- 11 mmHg, mean age of diabetes: 11 +/- 9 yr) without cardiovascular medications were recruited. Autonomic involvement was based on the results from a battery of five cardiovascular tests as suggested by Ewing. The result of each test and a scoring system was considered. All patients underwent power spectral analysis (PSA) of digital blood pressure (BP) and RR intervals recorded in the recumbent position and after tilting with a Finapres monitor. The percentage of total power (0.025-0.4 Hz) computed in the low-frequency band (0.070-0.139 Hz) computed in the low-frequency band (0.070-0.139 Hz) was chosen as a sympathetic index (sigma Ind). Results of tests were correlated with sigma Ind.

RESULTS

24 patients (39%) have an autonomic involvement. The most affected tests are: the Valsalva maneuver (VAL): 16% RR response from lying to standing (LS): 25%, sustained handgrip (SHG): 30%, postural hypotension (PH); 57%, deep breathing (DB): 87%. Correlations coefficients of cardiovascular tests and sigma Ind are: VAL/sigma Ind (SBP tilt): r = 0.277, p = 0.029; Val/sigma Ind (DBP tilt): r = 0.318, p = 0.012; VAL/sigma Ind (RR tilt): ns. PH/Ind sigma (SBP tilt): r = 0.391, p = 0.0017; PH/sigma Ind (DBP tilt): r = -0.296, p = 0.019; PH/sigma Ind (RR tilt): r = -0.308, p = 0.015, DB/sigma Ind (SBP tilt): r = 0.417, p = 0.0007; DB/sigma Ind (DBP tilt): r = 0.361, p = 0.0039; DB/sigma Ind (RR tilt): ns. Results of LS and SHG show no correlation with Ind sigma. Correlations between global autonomic score (GAS) and sigma Ind during tilting have the following values: GAS/sigma Ind (SBP tilt): r = -0486, p = 0.0001; GAS/sigma Ind (DBP tilt): r = -0.385, p = 0.002; GAS/sigma Ind (RR tilt): r = -0.411, p = 0.0009.

CONCLUSIONS

The so-called sympathetic index computed from PSA are well correlated with autonomic tests. They allow an early detection of sympathetic involvement in diabetics patients. These results are to consider while managing these subjects.

Authors+Show Affiliations

Service de pathologie cardiovasculaire, Hôpital d'Instruction des Armées Bégin, Saint-Mandé.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

fre

PubMed ID

8129517

Citation

Chanudet, X, et al. "[Comparative Evaluation of Diabetic Cardiac Autonomic Neuropathy By Spectrum Analysis and Ewing's Tests]." Archives Des Maladies Du Coeur Et Des Vaisseaux, vol. 86, no. 8, 1993, pp. 1143-8.
Chanudet X, Rabasa R, Chau NP, et al. [Comparative evaluation of diabetic cardiac autonomic neuropathy by spectrum analysis and Ewing's tests]. Arch Mal Coeur Vaiss. 1993;86(8):1143-8.
Chanudet, X., Rabasa, R., Chau, N. P., Bauduceau, B., Garcin, J. M., Gautier, D., & Larroque, P. (1993). [Comparative evaluation of diabetic cardiac autonomic neuropathy by spectrum analysis and Ewing's tests]. Archives Des Maladies Du Coeur Et Des Vaisseaux, 86(8), 1143-8.
Chanudet X, et al. [Comparative Evaluation of Diabetic Cardiac Autonomic Neuropathy By Spectrum Analysis and Ewing's Tests]. Arch Mal Coeur Vaiss. 1993;86(8):1143-8. PubMed PMID: 8129517.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Comparative evaluation of diabetic cardiac autonomic neuropathy by spectrum analysis and Ewing's tests]. AU - Chanudet,X, AU - Rabasa,R, AU - Chau,N P, AU - Bauduceau,B, AU - Garcin,J M, AU - Gautier,D, AU - Larroque,P, PY - 1993/8/1/pubmed PY - 1993/8/1/medline PY - 1993/8/1/entrez SP - 1143 EP - 8 JF - Archives des maladies du coeur et des vaisseaux JO - Arch Mal Coeur Vaiss VL - 86 IS - 8 N2 - METHODS: 62 diabetic patients of both sex (age: 46 +/- 16 yr, BMI: 26.1 +/- 4 kg/m2, casual blood pressure: 134 +/- 17/81 +/- 11 mmHg, mean age of diabetes: 11 +/- 9 yr) without cardiovascular medications were recruited. Autonomic involvement was based on the results from a battery of five cardiovascular tests as suggested by Ewing. The result of each test and a scoring system was considered. All patients underwent power spectral analysis (PSA) of digital blood pressure (BP) and RR intervals recorded in the recumbent position and after tilting with a Finapres monitor. The percentage of total power (0.025-0.4 Hz) computed in the low-frequency band (0.070-0.139 Hz) computed in the low-frequency band (0.070-0.139 Hz) was chosen as a sympathetic index (sigma Ind). Results of tests were correlated with sigma Ind. RESULTS: 24 patients (39%) have an autonomic involvement. The most affected tests are: the Valsalva maneuver (VAL): 16% RR response from lying to standing (LS): 25%, sustained handgrip (SHG): 30%, postural hypotension (PH); 57%, deep breathing (DB): 87%. Correlations coefficients of cardiovascular tests and sigma Ind are: VAL/sigma Ind (SBP tilt): r = 0.277, p = 0.029; Val/sigma Ind (DBP tilt): r = 0.318, p = 0.012; VAL/sigma Ind (RR tilt): ns. PH/Ind sigma (SBP tilt): r = 0.391, p = 0.0017; PH/sigma Ind (DBP tilt): r = -0.296, p = 0.019; PH/sigma Ind (RR tilt): r = -0.308, p = 0.015, DB/sigma Ind (SBP tilt): r = 0.417, p = 0.0007; DB/sigma Ind (DBP tilt): r = 0.361, p = 0.0039; DB/sigma Ind (RR tilt): ns. Results of LS and SHG show no correlation with Ind sigma. Correlations between global autonomic score (GAS) and sigma Ind during tilting have the following values: GAS/sigma Ind (SBP tilt): r = -0486, p = 0.0001; GAS/sigma Ind (DBP tilt): r = -0.385, p = 0.002; GAS/sigma Ind (RR tilt): r = -0.411, p = 0.0009. CONCLUSIONS: The so-called sympathetic index computed from PSA are well correlated with autonomic tests. They allow an early detection of sympathetic involvement in diabetics patients. These results are to consider while managing these subjects. SN - 0003-9683 UR - https://www.unboundmedicine.com/medline/citation/8129517/[Comparative_evaluation_of_diabetic_cardiac_autonomic_neuropathy_by_spectrum_analysis_and_Ewing's_tests]_ L2 - https://medlineplus.gov/diabeticnerveproblems.html DB - PRIME DP - Unbound Medicine ER -