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Chemical structure and conformational features of cell-wall polysaccharides isolated from Aphanoascus mephitalus and related species.
Carbohydr Res. 1993 Dec 28; 250(2):289-99.CR

Abstract

The structures of cell-wall mannans isolated from Aphanoascus mephitalus, A. fulvescens, A. verrucosus, and A. reticulisporus have been investigated by chemical analyses and 1D and 2D 1H and 13C NMR techniques. It was found that all of them consists of a relatively simple comb-like structure of the disaccharide repeating block [-->6)-[alpha-Manp-(1-->2)]-alpha-Manp-(1-->]. The conformations around the alpha-(1-->2) and alpha-(1-->6) linkages in these kinds of polymers were also studied by using molecular mechanics and dynamics calculations, together with NOE data. The results are similar to those found within the oligosaccharide chains of glycoproteins, with a well-defined conformation for the alpha-(1-->2) linkage and a certain restriction around the alpha-(1-->6) bonding imposed by the 2-substitution.

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Authors+Show Affiliations

Jiménez-Barbero J
Instituto de Química Orgánica, CSIC, Madrid, Spain.
Bernabé M
No affiliation info available
Leal JA
No affiliation info available
Prieto A
No affiliation info available
Gómez-Miranda B
No affiliation info available

MeSH

AscomycotaCarbohydrate ConformationCarbohydrate SequenceCell WallDisaccharidesMagnetic Resonance SpectroscopyMannansModels, MolecularMolecular Sequence DataPolysaccharidesSpecies Specificity

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8131160

Citation

Jiménez-Barbero, J, et al. "Chemical Structure and Conformational Features of Cell-wall Polysaccharides Isolated From Aphanoascus Mephitalus and Related Species." Carbohydrate Research, vol. 250, no. 2, 1993, pp. 289-99.
Jiménez-Barbero J, Bernabé M, Leal JA, et al. Chemical structure and conformational features of cell-wall polysaccharides isolated from Aphanoascus mephitalus and related species. Carbohydr Res. 1993;250(2):289-99.
Jiménez-Barbero, J., Bernabé, M., Leal, J. A., Prieto, A., & Gómez-Miranda, B. (1993). Chemical structure and conformational features of cell-wall polysaccharides isolated from Aphanoascus mephitalus and related species. Carbohydrate Research, 250(2), 289-99.
Jiménez-Barbero J, et al. Chemical Structure and Conformational Features of Cell-wall Polysaccharides Isolated From Aphanoascus Mephitalus and Related Species. Carbohydr Res. 1993 Dec 28;250(2):289-99. PubMed PMID: 8131160.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical structure and conformational features of cell-wall polysaccharides isolated from Aphanoascus mephitalus and related species. AU - Jiménez-Barbero,J, AU - Bernabé,M, AU - Leal,J A, AU - Prieto,A, AU - Gómez-Miranda,B, PY - 1993/12/28/pubmed PY - 1993/12/28/medline PY - 1993/12/28/entrez SP - 289 EP - 99 JF - Carbohydrate research JO - Carbohydr Res VL - 250 IS - 2 N2 - The structures of cell-wall mannans isolated from Aphanoascus mephitalus, A. fulvescens, A. verrucosus, and A. reticulisporus have been investigated by chemical analyses and 1D and 2D 1H and 13C NMR techniques. It was found that all of them consists of a relatively simple comb-like structure of the disaccharide repeating block [-->6)-[alpha-Manp-(1-->2)]-alpha-Manp-(1-->]. The conformations around the alpha-(1-->2) and alpha-(1-->6) linkages in these kinds of polymers were also studied by using molecular mechanics and dynamics calculations, together with NOE data. The results are similar to those found within the oligosaccharide chains of glycoproteins, with a well-defined conformation for the alpha-(1-->2) linkage and a certain restriction around the alpha-(1-->6) bonding imposed by the 2-substitution. SN - 0008-6215 UR - https://www.unboundmedicine.com/medline/citation/8131160/Chemical_structure_and_conformational_features_of_cell_wall_polysaccharides_isolated_from_Aphanoascus_mephitalus_and_related_species_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0008-6215(93)84007-S DB - PRIME DP - Unbound Medicine ER -