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[Diagnosis and surgical treatment for endocrine tumors of the pancreas].
Rinsho Byori. 1994 Feb; 42(2):150-9.RB

Abstract

Clinical features, diagnostic accuracy of imaging study, and the outcome of surgical treatment for endocrine tumors of the pancreas were analyzed in 12 patients who underwent surgery for the past 16 years and 11 months. The 12 cases were classified into two groups: functioning tumors in 8 (insulinoma in 7 including one malignant case, and malignant glucagonoma in one), and nonfunctioning tumors in 4 including 3 malignant cases. In functioning tumors, tumor size was 2 cm or less in 6 benign cases, but 5 cm or more in 2 malignant cases. In nonfunctioning tumors, tumor size was larger, ranging from 3.5 to 8.0 cm. Diagnostic accuracy for localization of functioning tumors was 66.7% for US, 75.0% for CT, 66.7% for endoscopic retrograde pancreatography (ERP), and 50.0% for selective angiography, while all nonfunctioning tumors could be detected by any diagnostic imagings. Percutaneous transhepatic portal venous sampling for immunoreactive insulin was very helpful to localize insulinoma. Stenosis or obstruction of the main pancreatic duct on ERP and arterial encasement on angiography highly suggested a malignant tumor. Even for malignant cases with liver metastasis, resection of the primary tumor with debulking of metastatic disease or intraarterial infusion chemotherapy was considered to prolong patient prognosis.

Authors+Show Affiliations

1st Department of Surgery, Mie University School of Medicine, Tsu.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

jpn

PubMed ID

8139124

Citation

Isaji, S, et al. "[Diagnosis and Surgical Treatment for Endocrine Tumors of the Pancreas]." Rinsho Byori. the Japanese Journal of Clinical Pathology, vol. 42, no. 2, 1994, pp. 150-9.
Isaji S, Kato K, Tanigawa K. [Diagnosis and surgical treatment for endocrine tumors of the pancreas]. Rinsho Byori. 1994;42(2):150-9.
Isaji, S., Kato, K., & Tanigawa, K. (1994). [Diagnosis and surgical treatment for endocrine tumors of the pancreas]. Rinsho Byori. the Japanese Journal of Clinical Pathology, 42(2), 150-9.
Isaji S, Kato K, Tanigawa K. [Diagnosis and Surgical Treatment for Endocrine Tumors of the Pancreas]. Rinsho Byori. 1994;42(2):150-9. PubMed PMID: 8139124.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Diagnosis and surgical treatment for endocrine tumors of the pancreas]. AU - Isaji,S, AU - Kato,K, AU - Tanigawa,K, PY - 1994/2/1/pubmed PY - 1994/2/1/medline PY - 1994/2/1/entrez SP - 150 EP - 9 JF - Rinsho byori. The Japanese journal of clinical pathology JO - Rinsho Byori VL - 42 IS - 2 N2 - Clinical features, diagnostic accuracy of imaging study, and the outcome of surgical treatment for endocrine tumors of the pancreas were analyzed in 12 patients who underwent surgery for the past 16 years and 11 months. The 12 cases were classified into two groups: functioning tumors in 8 (insulinoma in 7 including one malignant case, and malignant glucagonoma in one), and nonfunctioning tumors in 4 including 3 malignant cases. In functioning tumors, tumor size was 2 cm or less in 6 benign cases, but 5 cm or more in 2 malignant cases. In nonfunctioning tumors, tumor size was larger, ranging from 3.5 to 8.0 cm. Diagnostic accuracy for localization of functioning tumors was 66.7% for US, 75.0% for CT, 66.7% for endoscopic retrograde pancreatography (ERP), and 50.0% for selective angiography, while all nonfunctioning tumors could be detected by any diagnostic imagings. Percutaneous transhepatic portal venous sampling for immunoreactive insulin was very helpful to localize insulinoma. Stenosis or obstruction of the main pancreatic duct on ERP and arterial encasement on angiography highly suggested a malignant tumor. Even for malignant cases with liver metastasis, resection of the primary tumor with debulking of metastatic disease or intraarterial infusion chemotherapy was considered to prolong patient prognosis. SN - 0047-1860 UR - https://www.unboundmedicine.com/medline/citation/8139124/[Diagnosis_and_surgical_treatment_for_endocrine_tumors_of_the_pancreas]_ L2 - https://medlineplus.gov/pancreaticcancer.html DB - PRIME DP - Unbound Medicine ER -