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Breast biopsy: a comparative study of stereotaxically guided core and excisional techniques.
AJR Am J Roentgenol. 1994 Apr; 162(4):815-20.AA

Abstract

OBJECTIVE

The major objectives of this prospective study were to compare pathologic findings from stereotaxic core and excisional biopsies performed on patients with impalpable breast lesions and to compare the initial mammographic impression with the final histologic diagnosis.

SUBJECTS AND METHODS

All patients referred for preoperative localization of impalpable breast lesions between October 29, 1991, and January 15, 1993, were eligible for the study. If the patient and the lesion, on the basis of mammography, were considered suitable for core biopsy, the patient was asked to participate. Four hundred forty-five excisional biopsies were performed. One hundred sixty lesions were evaluated by core biopsy; for 104 of these lesions, five or more core samples were removed. Core biopsies were done with 14-gauge biopsy needles and were followed by a localization procedure. The pathologic features of core and excisional specimens were compared.

RESULTS

Biopsy results were compared for 93 (58%) benign and 67 (42%) malignant lesions. Of 104 lesions evaluated with at least five core specimens, 56 (54%) were benign and 48 (46%) were malignant. Results of core biopsy corresponded to those of excisional biopsy for 96% of benign lesions, 83% of malignant lesions, and 90% overall; sensitivity of core biopsy for malignant lesions was 85%. Of 56 lesions for which fewer than five core specimens were obtained, 37 (66%) were benign and 19 (34%) were malignant. Results of core biopsy corresponded to those of excisional biopsy for 81% of benign lesions, 79% of malignant lesions, and 80% overall; sensitivity of core biopsy for malignant lesions was 84%. Specificity of core biopsy for the entire series of benign lesions was 100%.

CONCLUSION

For mammographic lesions that are believed to be not malignant or not very likely malignant, stereotaxic core biopsy decreases the need for excisional biopsy.

Authors+Show Affiliations

Department of Diagnostic Radiology, Mayo Clinic, Rochester, MN 55905.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

8140997

Citation

Gisvold, J J., et al. "Breast Biopsy: a Comparative Study of Stereotaxically Guided Core and Excisional Techniques." AJR. American Journal of Roentgenology, vol. 162, no. 4, 1994, pp. 815-20.
Gisvold JJ, Goellner JR, Grant CS, et al. Breast biopsy: a comparative study of stereotaxically guided core and excisional techniques. AJR Am J Roentgenol. 1994;162(4):815-20.
Gisvold, J. J., Goellner, J. R., Grant, C. S., Donohue, J. H., Sykes, M. W., Karsell, P. R., Coffey, S. L., & Jung, S. H. (1994). Breast biopsy: a comparative study of stereotaxically guided core and excisional techniques. AJR. American Journal of Roentgenology, 162(4), 815-20.
Gisvold JJ, et al. Breast Biopsy: a Comparative Study of Stereotaxically Guided Core and Excisional Techniques. AJR Am J Roentgenol. 1994;162(4):815-20. PubMed PMID: 8140997.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Breast biopsy: a comparative study of stereotaxically guided core and excisional techniques. AU - Gisvold,J J, AU - Goellner,J R, AU - Grant,C S, AU - Donohue,J H, AU - Sykes,M W, AU - Karsell,P R, AU - Coffey,S L, AU - Jung,S H, PY - 1994/4/1/pubmed PY - 1994/4/1/medline PY - 1994/4/1/entrez SP - 815 EP - 20 JF - AJR. American journal of roentgenology JO - AJR Am J Roentgenol VL - 162 IS - 4 N2 - OBJECTIVE: The major objectives of this prospective study were to compare pathologic findings from stereotaxic core and excisional biopsies performed on patients with impalpable breast lesions and to compare the initial mammographic impression with the final histologic diagnosis. SUBJECTS AND METHODS: All patients referred for preoperative localization of impalpable breast lesions between October 29, 1991, and January 15, 1993, were eligible for the study. If the patient and the lesion, on the basis of mammography, were considered suitable for core biopsy, the patient was asked to participate. Four hundred forty-five excisional biopsies were performed. One hundred sixty lesions were evaluated by core biopsy; for 104 of these lesions, five or more core samples were removed. Core biopsies were done with 14-gauge biopsy needles and were followed by a localization procedure. The pathologic features of core and excisional specimens were compared. RESULTS: Biopsy results were compared for 93 (58%) benign and 67 (42%) malignant lesions. Of 104 lesions evaluated with at least five core specimens, 56 (54%) were benign and 48 (46%) were malignant. Results of core biopsy corresponded to those of excisional biopsy for 96% of benign lesions, 83% of malignant lesions, and 90% overall; sensitivity of core biopsy for malignant lesions was 85%. Of 56 lesions for which fewer than five core specimens were obtained, 37 (66%) were benign and 19 (34%) were malignant. Results of core biopsy corresponded to those of excisional biopsy for 81% of benign lesions, 79% of malignant lesions, and 80% overall; sensitivity of core biopsy for malignant lesions was 84%. Specificity of core biopsy for the entire series of benign lesions was 100%. CONCLUSION: For mammographic lesions that are believed to be not malignant or not very likely malignant, stereotaxic core biopsy decreases the need for excisional biopsy. SN - 0361-803X UR - https://www.unboundmedicine.com/medline/citation/8140997/Breast_biopsy:_a_comparative_study_of_stereotaxically_guided_core_and_excisional_techniques_ L2 - https://www.ajronline.org/doi/10.2214/ajr.162.4.8140997 DB - PRIME DP - Unbound Medicine ER -