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[Bronchial asthma caused by occupational sulfite exposure].
Allergol Immunopathol (Madr). 1993 Nov-Dec; 21(6):221-4.AI

Abstract

A case is reported of a patient with episodes of bronchospasm requiring hospital admission after handling sodium bisulfite on the job. The patient had a 15-year history of bronchial asthma and concomitant rhinoconjunctivitis and a 6-year history of asthma induced by moderate exercise. His family history included a father with sensitization to mites. Skin tests, measurement of specific IgI, and nasal provocation were positive for domestic dust mites and grass pollen. Skin tests for sodium metasulfite at a concentration of 10 mg/ml were negative. A simple blind oral provocation test of sodium metasulfite (1, 5, 20, and 50 mg) in acid medium was positive at the 50-mg dose, eliciting bronchial and nasal symptoms, and a decrease in CVF, FEV1, and PEF of more than 20% over baseline values. The episode of bronchospasm has not recurred in the workplace since exposure to sodium bisulfite was eliminated. Oral provocation with metasulfite in acid medium is considered a good technique for confirming the diagnosis of these cases.

Authors+Show Affiliations

Al.Lergo Centre, Barcelona.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

spa

PubMed ID

8160569

Citation

Valero, A L., et al. "[Bronchial Asthma Caused By Occupational Sulfite Exposure]." Allergologia Et Immunopathologia, vol. 21, no. 6, 1993, pp. 221-4.
Valero AL, Bescos M, Amat P, et al. [Bronchial asthma caused by occupational sulfite exposure]. Allergol Immunopathol (Madr). 1993;21(6):221-4.
Valero, A. L., Bescos, M., Amat, P., & Malet, A. (1993). [Bronchial asthma caused by occupational sulfite exposure]. Allergologia Et Immunopathologia, 21(6), 221-4.
Valero AL, et al. [Bronchial Asthma Caused By Occupational Sulfite Exposure]. Allergol Immunopathol (Madr). 1993;21(6):221-4. PubMed PMID: 8160569.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Bronchial asthma caused by occupational sulfite exposure]. AU - Valero,A L, AU - Bescos,M, AU - Amat,P, AU - Malet,A, PY - 1993/11/1/pubmed PY - 1993/11/1/medline PY - 1993/11/1/entrez SP - 221 EP - 4 JF - Allergologia et immunopathologia JO - Allergol Immunopathol (Madr) VL - 21 IS - 6 N2 - A case is reported of a patient with episodes of bronchospasm requiring hospital admission after handling sodium bisulfite on the job. The patient had a 15-year history of bronchial asthma and concomitant rhinoconjunctivitis and a 6-year history of asthma induced by moderate exercise. His family history included a father with sensitization to mites. Skin tests, measurement of specific IgI, and nasal provocation were positive for domestic dust mites and grass pollen. Skin tests for sodium metasulfite at a concentration of 10 mg/ml were negative. A simple blind oral provocation test of sodium metasulfite (1, 5, 20, and 50 mg) in acid medium was positive at the 50-mg dose, eliciting bronchial and nasal symptoms, and a decrease in CVF, FEV1, and PEF of more than 20% over baseline values. The episode of bronchospasm has not recurred in the workplace since exposure to sodium bisulfite was eliminated. Oral provocation with metasulfite in acid medium is considered a good technique for confirming the diagnosis of these cases. SN - 0301-0546 UR - https://www.unboundmedicine.com/medline/citation/8160569/[Bronchial_asthma_caused_by_occupational_sulfite_exposure]_ L2 - http://www.diseaseinfosearch.org/result/633 DB - PRIME DP - Unbound Medicine ER -