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Second cutaneous neoplasms after acute lymphoblastic leukemia in childhood.
Int J Hematol. 1993 Dec; 59(1):67-71.IJ

Abstract

Two cases of second cutaneous neoplasms, one with adenoid cystic carcinoma of the skin and the other with basal cell carcinoma, both occurring 7 years after treatment for childhood acute lymphoblastic leukemia (ALL) are reported. Although such cutaneous neoplasms are generally reported in patients over 40 years of age, our cases, which were diagnosed at the ages of 9 and 14, are the first report of the occurrence of such cutaneous neoplasms following ALL. The neoplasms arose from the scalp of two patients who had received cranial irradiation for central nervous system prophylaxis. The possible link between leukemia therapy incorporating irradiation and the pathogenesis of second cutaneous neoplasms in the scalp is discussed.

Authors+Show Affiliations

Yoshihara T
Division of Pediatrics, Kyoto First Red Cross Hospital, Japan.
Ikuta H
No affiliation info available
Hibi S
No affiliation info available
Todo S
No affiliation info available
Imashuku S
No affiliation info available

MeSH

Carcinoma, Adenoid CysticCarcinoma, Basal CellChildFemaleHumansNeoplasms, Second PrimaryPrecursor Cell Lymphoblastic Leukemia-LymphomaSkin Neoplasms

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

8161737

Citation

Yoshihara, T, et al. "Second Cutaneous Neoplasms After Acute Lymphoblastic Leukemia in Childhood." International Journal of Hematology, vol. 59, no. 1, 1993, pp. 67-71.
Yoshihara T, Ikuta H, Hibi S, et al. Second cutaneous neoplasms after acute lymphoblastic leukemia in childhood. Int J Hematol. 1993;59(1):67-71.
Yoshihara, T., Ikuta, H., Hibi, S., Todo, S., & Imashuku, S. (1993). Second cutaneous neoplasms after acute lymphoblastic leukemia in childhood. International Journal of Hematology, 59(1), 67-71.
Yoshihara T, et al. Second Cutaneous Neoplasms After Acute Lymphoblastic Leukemia in Childhood. Int J Hematol. 1993;59(1):67-71. PubMed PMID: 8161737.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Second cutaneous neoplasms after acute lymphoblastic leukemia in childhood. AU - Yoshihara,T, AU - Ikuta,H, AU - Hibi,S, AU - Todo,S, AU - Imashuku,S, PY - 1993/12/1/pubmed PY - 1993/12/1/medline PY - 1993/12/1/entrez SP - 67 EP - 71 JF - International journal of hematology JO - Int J Hematol VL - 59 IS - 1 N2 - Two cases of second cutaneous neoplasms, one with adenoid cystic carcinoma of the skin and the other with basal cell carcinoma, both occurring 7 years after treatment for childhood acute lymphoblastic leukemia (ALL) are reported. Although such cutaneous neoplasms are generally reported in patients over 40 years of age, our cases, which were diagnosed at the ages of 9 and 14, are the first report of the occurrence of such cutaneous neoplasms following ALL. The neoplasms arose from the scalp of two patients who had received cranial irradiation for central nervous system prophylaxis. The possible link between leukemia therapy incorporating irradiation and the pathogenesis of second cutaneous neoplasms in the scalp is discussed. SN - 0925-5710 UR - https://www.unboundmedicine.com/medline/citation/8161737/Second_cutaneous_neoplasms_after_acute_lymphoblastic_leukemia_in_childhood_ L2 - http://www.diseaseinfosearch.org/result/188 DB - PRIME DP - Unbound Medicine ER -