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Ascorbic acid effect on intestinal iron absorption in different types of anaemias.
Gaz Egypt Paediatr Assoc. 1975 Apr; 23(2):145-9.GE

Abstract

The study deals with investigations on anaemia due to iron or protein calorie deficiency and that associating acute glomerulonephritis, nephrosis and schistosoma haematobium. The rate of intestinal iron absorption using an oral dose of ferrous sulphate equivalent to 4 mg clemental iron/kg body weight was studied. The supplementing action of ascorbic acid in iron absorption in these cases was also investigated. The rate of intestinal iron absorption was enhanced in pure iron deficiency anaemia, acute glomerulonephritis and schistosoma haematobium, retarded in kwashiorkor, marasmus and nephrosis. Ascorbic acid markedly promoted iron absorption in normal subjects but slightly in pure iron deficiency anaemia. It improved iron absorption in acute glomerulonephritis and schistosoma haematobium but not in kwashiorkor, marasmus and nephrotic cases. It is concluded that ascorbic acid supplementation is of certain beneficial effect in alleviating the state of anaemia when intestinal iron absorption is not impaired. Also, it may prove to be of value to be given along with protein rehabilitation in anaemias associating protein deficiency.

Authors

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Pub Type(s)

Journal Article

Language

eng

PubMed ID

816695

Citation

El-Hawary, M F., et al. "Ascorbic Acid Effect On Intestinal Iron Absorption in Different Types of Anaemias." The Gazette of the Egyptian Paediatric Association, vol. 23, no. 2, 1975, pp. 145-9.
El-Hawary MF, El-Shobaki FA, Kholeif T, et al. Ascorbic acid effect on intestinal iron absorption in different types of anaemias. Gaz Egypt Paediatr Assoc. 1975;23(2):145-9.
El-Hawary, M. F., El-Shobaki, F. A., Kholeif, T., Sakr, R., El-Bassousy, E. M., Abdel-Khalek, K., & Khashaba, A. (1975). Ascorbic acid effect on intestinal iron absorption in different types of anaemias. The Gazette of the Egyptian Paediatric Association, 23(2), 145-9.
El-Hawary MF, et al. Ascorbic Acid Effect On Intestinal Iron Absorption in Different Types of Anaemias. Gaz Egypt Paediatr Assoc. 1975;23(2):145-9. PubMed PMID: 816695.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ascorbic acid effect on intestinal iron absorption in different types of anaemias. AU - El-Hawary,M F, AU - El-Shobaki,F A, AU - Kholeif,T, AU - Sakr,R, AU - El-Bassousy,E M, AU - Abdel-Khalek,K, AU - Khashaba,A, PY - 1975/4/1/pubmed PY - 1975/4/1/medline PY - 1975/4/1/entrez SP - 145 EP - 9 JF - The Gazette of the Egyptian Paediatric Association JO - Gaz Egypt Paediatr Assoc VL - 23 IS - 2 N2 - The study deals with investigations on anaemia due to iron or protein calorie deficiency and that associating acute glomerulonephritis, nephrosis and schistosoma haematobium. The rate of intestinal iron absorption using an oral dose of ferrous sulphate equivalent to 4 mg clemental iron/kg body weight was studied. The supplementing action of ascorbic acid in iron absorption in these cases was also investigated. The rate of intestinal iron absorption was enhanced in pure iron deficiency anaemia, acute glomerulonephritis and schistosoma haematobium, retarded in kwashiorkor, marasmus and nephrosis. Ascorbic acid markedly promoted iron absorption in normal subjects but slightly in pure iron deficiency anaemia. It improved iron absorption in acute glomerulonephritis and schistosoma haematobium but not in kwashiorkor, marasmus and nephrotic cases. It is concluded that ascorbic acid supplementation is of certain beneficial effect in alleviating the state of anaemia when intestinal iron absorption is not impaired. Also, it may prove to be of value to be given along with protein rehabilitation in anaemias associating protein deficiency. SN - 1110-6638 UR - https://www.unboundmedicine.com/medline/citation/816695/Ascorbic_acid_effect_on_intestinal_iron_absorption_in_different_types_of_anaemias_ L2 - https://medlineplus.gov/vitaminc.html DB - PRIME DP - Unbound Medicine ER -