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[Parenteral feeding. Biochemical and clinical findings during continuous long-term infusion of glucose, fructose, sorbitol and xylitol. 2. Clinical aspects, discussion and results].
Fortschr Med. 1975 Sep 25; 93(27):1257-61.FM

Abstract

Four groups of six volunteers were given continuous infusions of glucose, fructose, sorbitol and xylitol in a dosage of 0.25 g/kg body weight over 48 hours. All solutions were well tolerated provided that potassium was supplemented in sufficient amounts. During the first 12 hour period of xylitol infusion renal potassium loss was greater than during infusion of all other substrates. No substantial differences in the alterations of the other parameters were noted between glucose and glucose substitutes. The only exception was the rise in serum uric acid concentration during infusion of xylitol and of fructose, which was not noted during infusion of glucose or sorbitol. The concentration of serum bilirubin was elevated during infusion of all four substances. The decrease in serum free fatty acid concentration was equally caused by glucose, fructose, xylitol or sorbitol. The increase in serum triglyceride concentration was observed earlier during the infusion of glucose substitutes as compared to glucose. Blood glucose concentration was only elevated during infusion of glucose. In the post infusion period there was quick rise in fatty acid concentration after cessation of glucose infusion. This normalisation occurred more slowly after stopping fructose and particulary xylitol or sorbitol. These results have no indications for adverse effects of the continuous infusions of glucose or glucose substitutes.

Authors

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Pub Type(s)

English Abstract
Journal Article

Language

ger

PubMed ID

816722

Citation

Förster, H, et al. "[Parenteral Feeding. Biochemical and Clinical Findings During Continuous Long-term Infusion of Glucose, Fructose, Sorbitol and Xylitol. 2. Clinical Aspects, Discussion and Results]." Fortschritte Der Medizin, vol. 93, no. 27, 1975, pp. 1257-61.
Förster H, Heller L, Hellmund U, et al. [Parenteral feeding. Biochemical and clinical findings during continuous long-term infusion of glucose, fructose, sorbitol and xylitol. 2. Clinical aspects, discussion and results]. Fortschr Med. 1975;93(27):1257-61.
Förster, H., Heller, L., Hellmund, U., & Boecker, S. (1975). [Parenteral feeding. Biochemical and clinical findings during continuous long-term infusion of glucose, fructose, sorbitol and xylitol. 2. Clinical aspects, discussion and results]. Fortschritte Der Medizin, 93(27), 1257-61.
Förster H, et al. [Parenteral Feeding. Biochemical and Clinical Findings During Continuous Long-term Infusion of Glucose, Fructose, Sorbitol and Xylitol. 2. Clinical Aspects, Discussion and Results]. Fortschr Med. 1975 Sep 25;93(27):1257-61. PubMed PMID: 816722.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Parenteral feeding. Biochemical and clinical findings during continuous long-term infusion of glucose, fructose, sorbitol and xylitol. 2. Clinical aspects, discussion and results]. AU - Förster,H, AU - Heller,L, AU - Hellmund,U, AU - Boecker,S, PY - 1975/9/25/pubmed PY - 1975/9/25/medline PY - 1975/9/25/entrez SP - 1257 EP - 61 JF - Fortschritte der Medizin JO - Fortschr Med VL - 93 IS - 27 N2 - Four groups of six volunteers were given continuous infusions of glucose, fructose, sorbitol and xylitol in a dosage of 0.25 g/kg body weight over 48 hours. All solutions were well tolerated provided that potassium was supplemented in sufficient amounts. During the first 12 hour period of xylitol infusion renal potassium loss was greater than during infusion of all other substrates. No substantial differences in the alterations of the other parameters were noted between glucose and glucose substitutes. The only exception was the rise in serum uric acid concentration during infusion of xylitol and of fructose, which was not noted during infusion of glucose or sorbitol. The concentration of serum bilirubin was elevated during infusion of all four substances. The decrease in serum free fatty acid concentration was equally caused by glucose, fructose, xylitol or sorbitol. The increase in serum triglyceride concentration was observed earlier during the infusion of glucose substitutes as compared to glucose. Blood glucose concentration was only elevated during infusion of glucose. In the post infusion period there was quick rise in fatty acid concentration after cessation of glucose infusion. This normalisation occurred more slowly after stopping fructose and particulary xylitol or sorbitol. These results have no indications for adverse effects of the continuous infusions of glucose or glucose substitutes. SN - 0015-8178 UR - https://www.unboundmedicine.com/medline/citation/816722/[Parenteral_feeding__Biochemical_and_clinical_findings_during_continuous_long_term_infusion_of_glucose_fructose_sorbitol_and_xylitol__2__Clinical_aspects_discussion_and_results]_ DB - PRIME DP - Unbound Medicine ER -