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Red cell profile in normal and sickle cell diseased children.
J Egypt Soc Parasitol. 1994 Apr; 24(1):147-54.JE

Abstract

The red cell distribution width index (RDW) and other cell indices (HCT, MCV, MCH) were determined in 171 normal infants and children, 37 patients with sickle cell disease (SCD) and 44 patients with sickle cell trait (SCT). The red blood cell indices including RDW in normal children showed a significant difference between different age groups (P < 0.01), while in different sex groups, they did not differ significantly. SCD group showed a significant increase in RDW and a significant decrease in the hematocrit (HCT) value when compared either with the control or the SCT groups (P < 0.01). Patients with SCD showed a significant increase in their RDW and a significant decrease in their hematocrit values during haemolytic crises as compared with those during vaso-occlusive crises (P < 0.01). A positive linear correlation between RDW and the reticulocyte count in SCD and SCT patients. (r = .8842, P < 0.01) was also found. In this context it was concluded that RWD values do reflect the reticulocytes magnitude which would provide clinical and pathological information about SCD and its crises.

Authors+Show Affiliations

Department of Paediatrics and Clinical Pathology, Faculty of Medicine, Ain Shams University, Cairo.No affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8169436

Citation

el Sayed, H L., and Z M. Tawfik. "Red Cell Profile in Normal and Sickle Cell Diseased Children." Journal of the Egyptian Society of Parasitology, vol. 24, no. 1, 1994, pp. 147-54.
el Sayed HL, Tawfik ZM. Red cell profile in normal and sickle cell diseased children. J Egypt Soc Parasitol. 1994;24(1):147-54.
el Sayed, H. L., & Tawfik, Z. M. (1994). Red cell profile in normal and sickle cell diseased children. Journal of the Egyptian Society of Parasitology, 24(1), 147-54.
el Sayed HL, Tawfik ZM. Red Cell Profile in Normal and Sickle Cell Diseased Children. J Egypt Soc Parasitol. 1994;24(1):147-54. PubMed PMID: 8169436.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Red cell profile in normal and sickle cell diseased children. AU - el Sayed,H L, AU - Tawfik,Z M, PY - 1994/4/1/pubmed PY - 1994/4/1/medline PY - 1994/4/1/entrez SP - 147 EP - 54 JF - Journal of the Egyptian Society of Parasitology JO - J Egypt Soc Parasitol VL - 24 IS - 1 N2 - The red cell distribution width index (RDW) and other cell indices (HCT, MCV, MCH) were determined in 171 normal infants and children, 37 patients with sickle cell disease (SCD) and 44 patients with sickle cell trait (SCT). The red blood cell indices including RDW in normal children showed a significant difference between different age groups (P < 0.01), while in different sex groups, they did not differ significantly. SCD group showed a significant increase in RDW and a significant decrease in the hematocrit (HCT) value when compared either with the control or the SCT groups (P < 0.01). Patients with SCD showed a significant increase in their RDW and a significant decrease in their hematocrit values during haemolytic crises as compared with those during vaso-occlusive crises (P < 0.01). A positive linear correlation between RDW and the reticulocyte count in SCD and SCT patients. (r = .8842, P < 0.01) was also found. In this context it was concluded that RWD values do reflect the reticulocytes magnitude which would provide clinical and pathological information about SCD and its crises. SN - 1110-0583 UR - https://www.unboundmedicine.com/medline/citation/8169436/Red_cell_profile_in_normal_and_sickle_cell_diseased_children_ DB - PRIME DP - Unbound Medicine ER -