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Foods and additives are common causes of the attention deficit hyperactive disorder in children.

Abstract

The attention deficit hyperactive disorder (ADHD) is a neurophysiologic problem that is detrimental to children and their parents. Despite previous studies on the role of foods, preservatives and artificial colorings in ADHD this issue remains controversial. This investigation evaluated 26 children who meet the criteria for ADHD. Treatment with a multiple item elimination diet showed 19 children (73%) responded favorably, P < .001. On open challenge, all 19 children reacted to many foods, dyes, and/or preservatives. A double-blind placebo controlled food challenge (DBPCFC) was completed in 16 children. There was a significant improvement on placebo days compared with challenge days (P = .003). Atopic children with ADHD had a significantly higher response rate than the nonatopic group. This study demonstrates a beneficial effect of eliminating reactive foods and artificial colors in children with ADHD. Dietary factors may play a significant role in the etiology of the majority of children with ADHD.

Authors+Show Affiliations

,

North Shore Hospital-Cornell Medical Center, Manhasset, New York.

Source

Annals of allergy 72:5 1994 May pg 462-8

MeSH

Analysis of Variance
Attention Deficit Disorder with Hyperactivity
Child
Child, Preschool
Double-Blind Method
Female
Food
Food Additives
Food Hypersensitivity
Humans
Hypersensitivity, Immediate
Male
Placebos

Pub Type(s)

Clinical Trial
Controlled Clinical Trial
Journal Article
Randomized Controlled Trial
Review

Language

eng

PubMed ID

8179235

Citation

Boris, M, and F S. Mandel. "Foods and Additives Are Common Causes of the Attention Deficit Hyperactive Disorder in Children." Annals of Allergy, vol. 72, no. 5, 1994, pp. 462-8.
Boris M, Mandel FS. Foods and additives are common causes of the attention deficit hyperactive disorder in children. Ann Allergy. 1994;72(5):462-8.
Boris, M., & Mandel, F. S. (1994). Foods and additives are common causes of the attention deficit hyperactive disorder in children. Annals of Allergy, 72(5), pp. 462-8.
Boris M, Mandel FS. Foods and Additives Are Common Causes of the Attention Deficit Hyperactive Disorder in Children. Ann Allergy. 1994;72(5):462-8. PubMed PMID: 8179235.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Foods and additives are common causes of the attention deficit hyperactive disorder in children. AU - Boris,M, AU - Mandel,F S, PY - 1994/5/1/pubmed PY - 1994/5/1/medline PY - 1994/5/1/entrez SP - 462 EP - 8 JF - Annals of allergy JO - Ann Allergy VL - 72 IS - 5 N2 - The attention deficit hyperactive disorder (ADHD) is a neurophysiologic problem that is detrimental to children and their parents. Despite previous studies on the role of foods, preservatives and artificial colorings in ADHD this issue remains controversial. This investigation evaluated 26 children who meet the criteria for ADHD. Treatment with a multiple item elimination diet showed 19 children (73%) responded favorably, P < .001. On open challenge, all 19 children reacted to many foods, dyes, and/or preservatives. A double-blind placebo controlled food challenge (DBPCFC) was completed in 16 children. There was a significant improvement on placebo days compared with challenge days (P = .003). Atopic children with ADHD had a significantly higher response rate than the nonatopic group. This study demonstrates a beneficial effect of eliminating reactive foods and artificial colors in children with ADHD. Dietary factors may play a significant role in the etiology of the majority of children with ADHD. SN - 0003-4738 UR - https://www.unboundmedicine.com/medline/citation/8179235/Foods_and_additives_are_common_causes_of_the_attention_deficit_hyperactive_disorder_in_children_ L2 - http://www.diseaseinfosearch.org/result/659 DB - PRIME DP - Unbound Medicine ER -