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[Susceptibility of Clostridium difficile strains to teicoplanin and ramoplanin].
Med Dosw Mikrobiol. 1993; 45(4):483-6.MD

Abstract

The in vitro activity of teicoplanin and ramoplanin against 113 Clostridium difficile strains isolated from different origins was determined. The minimum inhibitory concentrations (MICs) of antibiotics were determined by the agar dilution method. MIC of teicoplanin and ramoplanin were twofold lower for Clostridium difficile strains isolated from patient with pseudomembranous colitis. No correlation between the origin of the strains toxigenicity and susceptibility to teicoplanin and ramoplanin was observed. Our result indicate that teicoplanin and ramoplanin are potentially effective alternative antibiotics for treatment of infections caused by Clostridium difficile.

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Authors+Show Affiliations

Dworczyński A
Zakład Bakteriologii Klinicznej AM w Warszawie.
Martirosian G
No affiliation info available
Meisel-Mikołajczyk F
No affiliation info available

MeSH

Anti-Bacterial AgentsClostridioides difficileDepsipeptidesEnterocolitis, PseudomembranousHumansPeptides, CyclicSpecies SpecificityTeicoplanin

Pub Type(s)

Journal Article

Language

pol

PubMed ID

8189828

Citation

Dworczyński, A, et al. "[Susceptibility of Clostridium Difficile Strains to Teicoplanin and Ramoplanin]." Medycyna Doswiadczalna I Mikrobiologia, vol. 45, no. 4, 1993, pp. 483-6.
Dworczyński A, Martirosian G, Meisel-Mikołajczyk F. [Susceptibility of Clostridium difficile strains to teicoplanin and ramoplanin]. Med Dosw Mikrobiol. 1993;45(4):483-6.
Dworczyński, A., Martirosian, G., & Meisel-Mikołajczyk, F. (1993). [Susceptibility of Clostridium difficile strains to teicoplanin and ramoplanin]. Medycyna Doswiadczalna I Mikrobiologia, 45(4), 483-6.
Dworczyński A, Martirosian G, Meisel-Mikołajczyk F. [Susceptibility of Clostridium Difficile Strains to Teicoplanin and Ramoplanin]. Med Dosw Mikrobiol. 1993;45(4):483-6. PubMed PMID: 8189828.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Susceptibility of Clostridium difficile strains to teicoplanin and ramoplanin]. AU - Dworczyński,A, AU - Martirosian,G, AU - Meisel-Mikołajczyk,F, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez SP - 483 EP - 6 JF - Medycyna doswiadczalna i mikrobiologia JO - Med Dosw Mikrobiol VL - 45 IS - 4 N2 - The in vitro activity of teicoplanin and ramoplanin against 113 Clostridium difficile strains isolated from different origins was determined. The minimum inhibitory concentrations (MICs) of antibiotics were determined by the agar dilution method. MIC of teicoplanin and ramoplanin were twofold lower for Clostridium difficile strains isolated from patient with pseudomembranous colitis. No correlation between the origin of the strains toxigenicity and susceptibility to teicoplanin and ramoplanin was observed. Our result indicate that teicoplanin and ramoplanin are potentially effective alternative antibiotics for treatment of infections caused by Clostridium difficile. SN - 0025-8601 UR - https://www.unboundmedicine.com/medline/citation/8189828/[Susceptibility_of_Clostridium_difficile_strains_to_teicoplanin_and_ramoplanin]_ L2 - http://www.diseaseinfosearch.org/result/1688 DB - PRIME DP - Unbound Medicine ER -