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The association of HLA-B5 antigen with specific manifestations of Behçet's disease.
Dermatology. 1994; 188(4):293-5.D

Abstract

The HLA-B5 phenotype was investigated in 235 patients with Behçet's disease and in 100 healthy persons. HLA-B5 was more frequent in the patients (77 vs. 30% p < 0.001, relative risk = 7.8). The frequency of HLA-B5 was higher in patients with genital ulceration than without (82.3 vs. 63%, p < 0.01). Patients with thrombophlebitis showed a less frequent positivity of HLA-B5 antigen than the patients without thrombophlebitis (50 vs. 79.2%, p < 0.02). These results suggest that HLA-B5-related genes not only affect the development of Behçet's disease but also the occurrence of its clinical manifestations.

Authors+Show Affiliations

Department of Dermatology, Istanbul Medical Faculty, Turkey.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8193403

Citation

Azizleri, G, et al. "The Association of HLA-B5 Antigen With Specific Manifestations of Behçet's Disease." Dermatology (Basel, Switzerland), vol. 188, no. 4, 1994, pp. 293-5.
Azizleri G, Aksungur VL, Sarica R, et al. The association of HLA-B5 antigen with specific manifestations of Behçet's disease. Dermatology (Basel). 1994;188(4):293-5.
Azizleri, G., Aksungur, V. L., Sarica, R., Akyol, E., & Ovül, C. (1994). The association of HLA-B5 antigen with specific manifestations of Behçet's disease. Dermatology (Basel, Switzerland), 188(4), 293-5.
Azizleri G, et al. The Association of HLA-B5 Antigen With Specific Manifestations of Behçet's Disease. Dermatology (Basel). 1994;188(4):293-5. PubMed PMID: 8193403.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The association of HLA-B5 antigen with specific manifestations of Behçet's disease. AU - Azizleri,G, AU - Aksungur,V L, AU - Sarica,R, AU - Akyol,E, AU - Ovül,C, PY - 1994/1/1/pubmed PY - 1994/1/1/medline PY - 1994/1/1/entrez SP - 293 EP - 5 JF - Dermatology (Basel, Switzerland) JO - Dermatology (Basel) VL - 188 IS - 4 N2 - The HLA-B5 phenotype was investigated in 235 patients with Behçet's disease and in 100 healthy persons. HLA-B5 was more frequent in the patients (77 vs. 30% p < 0.001, relative risk = 7.8). The frequency of HLA-B5 was higher in patients with genital ulceration than without (82.3 vs. 63%, p < 0.01). Patients with thrombophlebitis showed a less frequent positivity of HLA-B5 antigen than the patients without thrombophlebitis (50 vs. 79.2%, p < 0.02). These results suggest that HLA-B5-related genes not only affect the development of Behçet's disease but also the occurrence of its clinical manifestations. SN - 1018-8665 UR - https://www.unboundmedicine.com/medline/citation/8193403/The_association_of_HLA_B5_antigen_with_specific_manifestations_of_Behçet's_disease_ L2 - https://www.karger.com?DOI=10.1159/000247169 DB - PRIME DP - Unbound Medicine ER -