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[A case of multiple myeloma associated with a large subcutaneous mass in the frontal region].
No Shinkei Geka. 1994 May; 22(5):455-60.NS

Abstract

A case of multiple myeloma having plasmacytoma in the frontal bone and clivus is reported. A 68-year-old female was referred to our hospital because of a subcutaneous mass in the frontal region. She was diagnosed as having multiple myeloma 7 years ago and had been treated with chemotherapy. On admission, severe anemia, hyperproteinemia and elevation of serum lambda type immunoglobulin G (IgG) were pointed out. Plain skull X-rays showed numerous punched out lesions with a large bone defect of the frontal bone. CT scan and MRI revealed a mass lesion in the clivus in addition to a large epidural tumor in the frontal region. The encapsulated frontal epidural tumor was totally resected and cranioplasty was performed with resin. Histological diagnosis was plasmacytoma of IgG lambda type. The postoperative course was uneventful, and chemotherapy was continued. There was no tumor recurrence in the frontal region and no neurological deterioration, but she died of DIC 15 months after the operation. Twenty seven cases in the literature of multiple myeloma forming cranial or intracranial plasmacytoma were briefly reviewed. Although the prognosis of such cases is poor, total resection of medullary plasmacytoma is warranted especially in multiple myeloma patients who don't have another extramedullary plasmacytoma or plasma cell leukemia.

Authors+Show Affiliations

Department of Neurosurgery, Nagasaki-chuo National Hospital, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
English Abstract
Journal Article
Review

Language

jpn

PubMed ID

8196832

Citation

Anda, T, et al. "[A Case of Multiple Myeloma Associated With a Large Subcutaneous Mass in the Frontal Region]." No Shinkei Geka. Neurological Surgery, vol. 22, no. 5, 1994, pp. 455-60.
Anda T, Baba H, Yonekura M, et al. [A case of multiple myeloma associated with a large subcutaneous mass in the frontal region]. No Shinkei Geka. 1994;22(5):455-60.
Anda, T., Baba, H., Yonekura, M., Moriyama, T., Teramoto, S., & Fujii, H. (1994). [A case of multiple myeloma associated with a large subcutaneous mass in the frontal region]. No Shinkei Geka. Neurological Surgery, 22(5), 455-60.
Anda T, et al. [A Case of Multiple Myeloma Associated With a Large Subcutaneous Mass in the Frontal Region]. No Shinkei Geka. 1994;22(5):455-60. PubMed PMID: 8196832.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [A case of multiple myeloma associated with a large subcutaneous mass in the frontal region]. AU - Anda,T, AU - Baba,H, AU - Yonekura,M, AU - Moriyama,T, AU - Teramoto,S, AU - Fujii,H, PY - 1994/5/1/pubmed PY - 1994/5/1/medline PY - 1994/5/1/entrez SP - 455 EP - 60 JF - No shinkei geka. Neurological surgery JO - No Shinkei Geka VL - 22 IS - 5 N2 - A case of multiple myeloma having plasmacytoma in the frontal bone and clivus is reported. A 68-year-old female was referred to our hospital because of a subcutaneous mass in the frontal region. She was diagnosed as having multiple myeloma 7 years ago and had been treated with chemotherapy. On admission, severe anemia, hyperproteinemia and elevation of serum lambda type immunoglobulin G (IgG) were pointed out. Plain skull X-rays showed numerous punched out lesions with a large bone defect of the frontal bone. CT scan and MRI revealed a mass lesion in the clivus in addition to a large epidural tumor in the frontal region. The encapsulated frontal epidural tumor was totally resected and cranioplasty was performed with resin. Histological diagnosis was plasmacytoma of IgG lambda type. The postoperative course was uneventful, and chemotherapy was continued. There was no tumor recurrence in the frontal region and no neurological deterioration, but she died of DIC 15 months after the operation. Twenty seven cases in the literature of multiple myeloma forming cranial or intracranial plasmacytoma were briefly reviewed. Although the prognosis of such cases is poor, total resection of medullary plasmacytoma is warranted especially in multiple myeloma patients who don't have another extramedullary plasmacytoma or plasma cell leukemia. SN - 0301-2603 UR - https://www.unboundmedicine.com/medline/citation/8196832/[A_case_of_multiple_myeloma_associated_with_a_large_subcutaneous_mass_in_the_frontal_region]_ L2 - http://www.diseaseinfosearch.org/result/4962 DB - PRIME DP - Unbound Medicine ER -