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Urinary calcium oxalate saturation in 'stone formers' and normal subjects: an application of the EQUIL2 program.
Br J Urol. 1994 Apr; 73(4):358-61.BJ

Abstract

OBJECTIVE

To produce an index of lithogenic risk which identifies patients at risk of stone recurrence and facilitates the monitoring of prophylactic treatments.

PATIENTS AND METHODS

The EQUIL2 program provides an evaluation of the state of urinary saturation, particularly of calcium oxalate, based on the pH and total concentrations (mmol/l) of sodium, potassium, calcium, magnesium, uric acid, chloride, ammonium, citrate, phosphate, sulphate, oxalate, pyrophosphate and carbon dioxide. The morning urinary calcium oxalate saturation coefficient was thus calculated for 30 stone-formers (Group 1) and 30 normal control subjects (Group 2).

RESULTS

Urine from the majority of individuals was saturated, with no significant difference between the two groups. There appeared to be a correlation between the state of saturation and the urinary calcium oxalate molar product in both stone-formers (r = 0.931) and controls (r = 0.914).

CONCLUSION

In future studies on urinary calcium oxalate saturation, it should be possible to supplement the sophisticated coefficient determined by the EQUIL2 program with the molar product, except in cases where monitoring therapies have little or no effect on urinary oxalate or urinary calcium levels.

Authors+Show Affiliations

Department of Urology, Lapeyronie Hospital, Montpellier, France.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8199821

Citation

Robert, M, et al. "Urinary Calcium Oxalate Saturation in 'stone Formers' and Normal Subjects: an Application of the EQUIL2 Program." British Journal of Urology, vol. 73, no. 4, 1994, pp. 358-61.
Robert M, Boularan AM, Colette C, et al. Urinary calcium oxalate saturation in 'stone formers' and normal subjects: an application of the EQUIL2 program. Br J Urol. 1994;73(4):358-61.
Robert, M., Boularan, A. M., Colette, C., Averous, M., & Monnier, L. (1994). Urinary calcium oxalate saturation in 'stone formers' and normal subjects: an application of the EQUIL2 program. British Journal of Urology, 73(4), 358-61.
Robert M, et al. Urinary Calcium Oxalate Saturation in 'stone Formers' and Normal Subjects: an Application of the EQUIL2 Program. Br J Urol. 1994;73(4):358-61. PubMed PMID: 8199821.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Urinary calcium oxalate saturation in 'stone formers' and normal subjects: an application of the EQUIL2 program. AU - Robert,M, AU - Boularan,A M, AU - Colette,C, AU - Averous,M, AU - Monnier,L, PY - 1994/4/1/pubmed PY - 1994/4/1/medline PY - 1994/4/1/entrez SP - 358 EP - 61 JF - British journal of urology JO - Br J Urol VL - 73 IS - 4 N2 - OBJECTIVE: To produce an index of lithogenic risk which identifies patients at risk of stone recurrence and facilitates the monitoring of prophylactic treatments. PATIENTS AND METHODS: The EQUIL2 program provides an evaluation of the state of urinary saturation, particularly of calcium oxalate, based on the pH and total concentrations (mmol/l) of sodium, potassium, calcium, magnesium, uric acid, chloride, ammonium, citrate, phosphate, sulphate, oxalate, pyrophosphate and carbon dioxide. The morning urinary calcium oxalate saturation coefficient was thus calculated for 30 stone-formers (Group 1) and 30 normal control subjects (Group 2). RESULTS: Urine from the majority of individuals was saturated, with no significant difference between the two groups. There appeared to be a correlation between the state of saturation and the urinary calcium oxalate molar product in both stone-formers (r = 0.931) and controls (r = 0.914). CONCLUSION: In future studies on urinary calcium oxalate saturation, it should be possible to supplement the sophisticated coefficient determined by the EQUIL2 program with the molar product, except in cases where monitoring therapies have little or no effect on urinary oxalate or urinary calcium levels. SN - 0007-1331 UR - https://www.unboundmedicine.com/medline/citation/8199821/Urinary_calcium_oxalate_saturation_in_'stone_formers'_and_normal_subjects:_an_application_of_the_EQUIL2_program_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0007-1331&date=1994&volume=73&issue=4&spage=358 DB - PRIME DP - Unbound Medicine ER -