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Solid breast lesions: diagnosis with US-guided fine-needle aspiration biopsy.
Radiology. 1993 Nov; 189(2):573-80.R

Abstract

PURPOSE

To ascertain the usefulness of real-time ultrasound (US)-guided fine-needle aspiration biopsy as an adjunct to clinical, mammographic, and sonographic assessment of solid breast lesions.

MATERIALS AND METHODS

US-guided fine-needle aspiration biopsy was performed in 225 malignant and 580 benign solid breast lesions confirmed by means of excisional biopsy or with imaging follow-up (mammography or US) performed at approximate intervals of 6, 12, 24, and 36 months. All lesions were classified as palpable or nonpalpable at clinical examination and visible or nonvisible on mammograms.

RESULTS

In 213 malignant lesions (95%), the cytologic findings were malignant or suspicious, with no false-positive and 12 false-negative cases. Mammography did not enable detection of 58 cancers (26%), 43 of which were palpable. Fifteen cancers discovered with US were nonpalpable and not seen on mammograms. Cytologic diagnosis of fibroadenoma or nonspecific benign cells was correct in 535 lesions. The sensitivity of this method was 95%; specificity, 92%; and overall accuracy, 93%.

CONCLUSION

Real-time US-guided fine-needle aspiration biopsy is a useful adjunct to clinical, mammographic, and sonographic assessment of solid breast lesions.

Authors+Show Affiliations

Department of Radiology, University of British Columbia, Vancouver, Canada.No affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8210392

Citation

Gordon, P B., et al. "Solid Breast Lesions: Diagnosis With US-guided Fine-needle Aspiration Biopsy." Radiology, vol. 189, no. 2, 1993, pp. 573-80.
Gordon PB, Goldenberg SL, Chan NH. Solid breast lesions: diagnosis with US-guided fine-needle aspiration biopsy. Radiology. 1993;189(2):573-80.
Gordon, P. B., Goldenberg, S. L., & Chan, N. H. (1993). Solid breast lesions: diagnosis with US-guided fine-needle aspiration biopsy. Radiology, 189(2), 573-80.
Gordon PB, Goldenberg SL, Chan NH. Solid Breast Lesions: Diagnosis With US-guided Fine-needle Aspiration Biopsy. Radiology. 1993;189(2):573-80. PubMed PMID: 8210392.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Solid breast lesions: diagnosis with US-guided fine-needle aspiration biopsy. AU - Gordon,P B, AU - Goldenberg,S L, AU - Chan,N H, PY - 1993/11/1/pubmed PY - 1993/11/1/medline PY - 1993/11/1/entrez SP - 573 EP - 80 JF - Radiology JO - Radiology VL - 189 IS - 2 N2 - PURPOSE: To ascertain the usefulness of real-time ultrasound (US)-guided fine-needle aspiration biopsy as an adjunct to clinical, mammographic, and sonographic assessment of solid breast lesions. MATERIALS AND METHODS: US-guided fine-needle aspiration biopsy was performed in 225 malignant and 580 benign solid breast lesions confirmed by means of excisional biopsy or with imaging follow-up (mammography or US) performed at approximate intervals of 6, 12, 24, and 36 months. All lesions were classified as palpable or nonpalpable at clinical examination and visible or nonvisible on mammograms. RESULTS: In 213 malignant lesions (95%), the cytologic findings were malignant or suspicious, with no false-positive and 12 false-negative cases. Mammography did not enable detection of 58 cancers (26%), 43 of which were palpable. Fifteen cancers discovered with US were nonpalpable and not seen on mammograms. Cytologic diagnosis of fibroadenoma or nonspecific benign cells was correct in 535 lesions. The sensitivity of this method was 95%; specificity, 92%; and overall accuracy, 93%. CONCLUSION: Real-time US-guided fine-needle aspiration biopsy is a useful adjunct to clinical, mammographic, and sonographic assessment of solid breast lesions. SN - 0033-8419 UR - https://www.unboundmedicine.com/medline/citation/8210392/Solid_breast_lesions:_diagnosis_with_US_guided_fine_needle_aspiration_biopsy_ L2 - https://pubs.rsna.org/doi/10.1148/radiology.189.2.8210392?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -