[Studies on the chemical constituents of Lonicera macranthoides Hand. -Mazz].
Yao Xue Xue Bao. 1993; 28(4):273-81.YX

Abstract

Three bisdesmosidic triterpenoid saponins I-III, have been isolated from the flowers of Lonicera macranthoides Hand. -Mazz. By spectral (IR, MS, 1H-NMR and 13C-NMR) and chemical methods, I was proved to be identical with the known dipsacoside B, II and III were new compounds named macranthoidin A and macranthoidin B. Their structures were identified as follows: The prosapogenin of II, macranthoside A(IIb), was elucidated as 3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-2)-alpha-L- arabinopyranosyl 3 beta, 23-dihydroxyl-olean-12-en-28-olic acid, II was established as 3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-2)-alpha-L- arabinopyranosyl 3 beta,23-dihydroxyl-olean-12-en-28-O-beta-D-glucopyranosyl-(1-6)-beta-D- glucopyranoside. The prosapogenin of III, macranthoside B(IIIb), was elucidated as 3-O-beta-D-glucopyranosyl-(1-4)-beta-D-glucopyranosyl-(1-3)-alpha-L- rhamnopyranosyl-(1-2)-alpha-L-arabinopyranosyl 3 beta,23-dihydroxyl-olean-12-en-28-olic acid, III was established as 3-O-beta-D-glucopyranosyl-(1-4)-beta-D-glucopyranosyl-(1-3)-alpha-L- rhamnopyranosyl-(1-2)-alpha-L-arabinopyranosyl 3 beta,23-dihydroxyl-olean-12-en-28-O-beta-D-glucopyranosyl-(1-6)-beta-D- glucopyranoside. IIb and IIIb have not been reported in the literature.

Authors+Show Affiliations

Mao Q

Guizhou Institute of Traditional Chinese Medicine, Guiyang.

Cao D

No affiliation info available

Jia XS

No affiliation info available

MeSH

Drugs, Chinese HerbalOleanolic AcidSaponinsTriterpenes

Pub Type(s)

English Abstract

Journal Article

Language

chi

PubMed ID

8213170

Citation

Mao, Q, et al. "[Studies On the Chemical Constituents of Lonicera Macranthoides Hand. -Mazz]." Yao Xue Xue Bao = Acta Pharmaceutica Sinica, vol. 28, no. 4, 1993, pp. 273-81.

Mao Q, Cao D, Jia XS. [Studies on the chemical constituents of Lonicera macranthoides Hand. -Mazz]. Yao Xue Xue Bao. 1993;28(4):273-81.

Mao, Q., Cao, D., & Jia, X. S. (1993). [Studies on the chemical constituents of Lonicera macranthoides Hand. -Mazz]. Yao Xue Xue Bao = Acta Pharmaceutica Sinica, 28(4), 273-81.

Mao Q, Cao D, Jia XS. [Studies On the Chemical Constituents of Lonicera Macranthoides Hand. -Mazz]. Yao Xue Xue Bao. 1993;28(4):273-81. PubMed PMID: 8213170.

* Article titles in AMA citation format should be in sentence-case

TY - JOUR T1 - [Studies on the chemical constituents of Lonicera macranthoides Hand. -Mazz]. AU - Mao,Q, AU - Cao,D, AU - Jia,X S, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez SP - 273 EP - 81 JF - Yao xue xue bao = Acta pharmaceutica Sinica JO - Yao Xue Xue Bao VL - 28 IS - 4 N2 - Three bisdesmosidic triterpenoid saponins I-III, have been isolated from the flowers of Lonicera macranthoides Hand. -Mazz. By spectral (IR, MS, 1H-NMR and 13C-NMR) and chemical methods, I was proved to be identical with the known dipsacoside B, II and III were new compounds named macranthoidin A and macranthoidin B. Their structures were identified as follows: The prosapogenin of II, macranthoside A(IIb), was elucidated as 3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-2)-alpha-L- arabinopyranosyl 3 beta, 23-dihydroxyl-olean-12-en-28-olic acid, II was established as 3-O-beta-D-glucopyranosyl-(1-3)-alpha-L-rhamnopyranosyl-(1-2)-alpha-L- arabinopyranosyl 3 beta,23-dihydroxyl-olean-12-en-28-O-beta-D-glucopyranosyl-(1-6)-beta-D- glucopyranoside. The prosapogenin of III, macranthoside B(IIIb), was elucidated as 3-O-beta-D-glucopyranosyl-(1-4)-beta-D-glucopyranosyl-(1-3)-alpha-L- rhamnopyranosyl-(1-2)-alpha-L-arabinopyranosyl 3 beta,23-dihydroxyl-olean-12-en-28-olic acid, III was established as 3-O-beta-D-glucopyranosyl-(1-4)-beta-D-glucopyranosyl-(1-3)-alpha-L- rhamnopyranosyl-(1-2)-alpha-L-arabinopyranosyl 3 beta,23-dihydroxyl-olean-12-en-28-O-beta-D-glucopyranosyl-(1-6)-beta-D- glucopyranoside. IIb and IIIb have not been reported in the literature. SN - 0513-4870 UR - https://www.unboundmedicine.com/medline/citation/8213170/[Studies_on_the_chemical_constituents_of_Lonicera_macranthoides_Hand___Mazz]_ DB - PRIME DP - Unbound Medicine ER -

Tags

[Studies on the chemical constituents of Lonicera macranthoides Hand. -Mazz].Yao Xue Xue Bao. 1993; 28(4):273-81.YX