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[Clinical treatment of peripheral arterial occlusive diseases].
Fortschr Med. 1976 Sep 23; 94(27):1500-4.FM

Abstract

Effectiveness and tolerance of Defluina was studied in a selective open trial including 30 patients (17 males, 13 females, mean age 70 years) suffering from peripheral arterial occlusive diseases of different stages. All patients were treated with Defluina, 20 drops thrice a day during a mean period of 30 days. Simultaneous application of further peripheral vasodilators was excluded. Subjective and objective parameters (pulse, Ratschow's test, walking distance) of 27 patients (15 males, 12 females) were evaluated. After 4 weeks of therapy an improvement of all parameters especially of the walking distance was observed. Within 4 weeks 3 of 5 ulcera cruris as well as an initially existing gangrene were closed. Deflunia was well tolerated by 25 patients, very well tolerated by 2. The therapy was discontinued in 3 patients: 2 because of unchanged complaints after 13 and 20 days of therapy, 1 after 17 days due to dull gastric pain following intake of the drug. Cardiac side-effects or steal phenomena were not observed.

Authors

No affiliation info available

Pub Type(s)

Clinical Trial
English Abstract
Journal Article

Language

ger

PubMed ID

823087

Citation

Schulte, B. "[Clinical Treatment of Peripheral Arterial Occlusive Diseases]." Fortschritte Der Medizin, vol. 94, no. 27, 1976, pp. 1500-4.
Schulte B. [Clinical treatment of peripheral arterial occlusive diseases]. Fortschr Med. 1976;94(27):1500-4.
Schulte, B. (1976). [Clinical treatment of peripheral arterial occlusive diseases]. Fortschritte Der Medizin, 94(27), 1500-4.
Schulte B. [Clinical Treatment of Peripheral Arterial Occlusive Diseases]. Fortschr Med. 1976 Sep 23;94(27):1500-4. PubMed PMID: 823087.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinical treatment of peripheral arterial occlusive diseases]. A1 - Schulte,B, PY - 1976/9/23/pubmed PY - 1976/9/23/medline PY - 1976/9/23/entrez SP - 1500 EP - 4 JF - Fortschritte der Medizin JO - Fortschr. Med. VL - 94 IS - 27 N2 - Effectiveness and tolerance of Defluina was studied in a selective open trial including 30 patients (17 males, 13 females, mean age 70 years) suffering from peripheral arterial occlusive diseases of different stages. All patients were treated with Defluina, 20 drops thrice a day during a mean period of 30 days. Simultaneous application of further peripheral vasodilators was excluded. Subjective and objective parameters (pulse, Ratschow's test, walking distance) of 27 patients (15 males, 12 females) were evaluated. After 4 weeks of therapy an improvement of all parameters especially of the walking distance was observed. Within 4 weeks 3 of 5 ulcera cruris as well as an initially existing gangrene were closed. Deflunia was well tolerated by 25 patients, very well tolerated by 2. The therapy was discontinued in 3 patients: 2 because of unchanged complaints after 13 and 20 days of therapy, 1 after 17 days due to dull gastric pain following intake of the drug. Cardiac side-effects or steal phenomena were not observed. SN - 0015-8178 UR - https://www.unboundmedicine.com/medline/citation/823087/[Clinical_treatment_of_peripheral_arterial_occlusive_diseases]_ DB - PRIME DP - Unbound Medicine ER -