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Intestinal adaptation after extensive resection of the small intestine and prolonged administration of parenteral nutrition.
Surg Gynecol Obstet. 1976 Nov; 143(5):757-62.SG

Abstract

After a superior mesenteric thrombosis in a 77 year old man, all but 24 centimeters of the jejunum were resected and anastomosed to the remaining left colon. After being maintained on parenteral nutrition on a 24 hour basis for six weeks, the patient was placed on overnight parenteral nutrition in which he received 2 liters of parenteral nutrition solution containing about 2,200 calories. Over a period of nine months, hypertrophy, lengthening and dilatation took place so that the patient was almost able to support himself by mouth. We believe that this is the first patient in whom documented lengthening of the small intestine has been reported. The factors entering into the hypertrophy and dilatation are discussed. Many patients in this age group are denied therapy because of the consequences of massive enterectomy. With adaptation using prolonged parenteral nutrition, it should be possible for most patients to sustain themselves completely by mouth. Patients with massive necrosis of the small intestine should not be denied therapy even if only 1 foot of small intestine remains. This is likely to hypertrophy in length until parenteral nutrition is no longer necessary.

Authors

Scheflan M
No affiliation info available
Galli SJ
No affiliation info available
Perrotto J
No affiliation info available
Fischer JE
No affiliation info available

MeSH

Adaptation, PhysiologicalAgedHumansIntestine, SmallJejunumMaleMesenteric Vascular OcclusionNecrosisParenteral NutritionParenteral Nutrition, TotalPostoperative CareTime Factors

Pub Type(s)

Case Reports
Journal Article

Language

eng

PubMed ID

824751

Citation

Scheflan, M, et al. "Intestinal Adaptation After Extensive Resection of the Small Intestine and Prolonged Administration of Parenteral Nutrition." Surgery, Gynecology & Obstetrics, vol. 143, no. 5, 1976, pp. 757-62.
Scheflan M, Galli SJ, Perrotto J, et al. Intestinal adaptation after extensive resection of the small intestine and prolonged administration of parenteral nutrition. Surg Gynecol Obstet. 1976;143(5):757-62.
Scheflan, M., Galli, S. J., Perrotto, J., & Fischer, J. E. (1976). Intestinal adaptation after extensive resection of the small intestine and prolonged administration of parenteral nutrition. Surgery, Gynecology & Obstetrics, 143(5), 757-62.
Scheflan M, et al. Intestinal Adaptation After Extensive Resection of the Small Intestine and Prolonged Administration of Parenteral Nutrition. Surg Gynecol Obstet. 1976;143(5):757-62. PubMed PMID: 824751.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Intestinal adaptation after extensive resection of the small intestine and prolonged administration of parenteral nutrition. AU - Scheflan,M, AU - Galli,S J, AU - Perrotto,J, AU - Fischer,J E, PY - 1976/11/1/pubmed PY - 1976/11/1/medline PY - 1976/11/1/entrez SP - 757 EP - 62 JF - Surgery, gynecology & obstetrics JO - Surg Gynecol Obstet VL - 143 IS - 5 N2 - After a superior mesenteric thrombosis in a 77 year old man, all but 24 centimeters of the jejunum were resected and anastomosed to the remaining left colon. After being maintained on parenteral nutrition on a 24 hour basis for six weeks, the patient was placed on overnight parenteral nutrition in which he received 2 liters of parenteral nutrition solution containing about 2,200 calories. Over a period of nine months, hypertrophy, lengthening and dilatation took place so that the patient was almost able to support himself by mouth. We believe that this is the first patient in whom documented lengthening of the small intestine has been reported. The factors entering into the hypertrophy and dilatation are discussed. Many patients in this age group are denied therapy because of the consequences of massive enterectomy. With adaptation using prolonged parenteral nutrition, it should be possible for most patients to sustain themselves completely by mouth. Patients with massive necrosis of the small intestine should not be denied therapy even if only 1 foot of small intestine remains. This is likely to hypertrophy in length until parenteral nutrition is no longer necessary. SN - 0039-6087 UR - https://www.unboundmedicine.com/medline/citation/824751/Intestinal_adaptation_after_extensive_resection_of_the_small_intestine_and_prolonged_administration_of_parenteral_nutrition_ DB - PRIME DP - Unbound Medicine ER -