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Postprandial gastric motility in infants with gastroesophageal reflux and delayed gastric emptying.
J Nucl Med. 1993 Dec; 34(12):2120-3.JN

Abstract

Delayed gastric emptying of formula is observed in many infants with gastroesophageal reflux but the mechanisms responsible for this observation are not defined. Postprandial gastric motility was quantified using a perfused catheter placed into the distal stomach of five infants with gastroesophageal reflux and delayed gastric emptying of 99mTc-sulfur colloid-labeled formula. Five infants with reflux who exhibited normal emptying of formula served as the controls. Gastric motility indices were calculated for 60 min following a meal. Half the patients in each group were given metoclopramide following a 30-min recording period. In both groups, postprandial gastric motility was similar and characterized by minimal gastric contractions. Metoclopramide resulted in increased amplitude and duration of antral contractions, but no significant differences were noted between groups. The findings suggest that minimal delays in gastric emptying in infants with gastroesophageal reflux are not associated with significant alterations of postprandial gastric motility.

Authors+Show Affiliations

Department of Pediatrics, School of Medicine, University of California, Davis.No affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

8254398

Citation

Cannon, R A., and R C. Stadalnik. "Postprandial Gastric Motility in Infants With Gastroesophageal Reflux and Delayed Gastric Emptying." Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, vol. 34, no. 12, 1993, pp. 2120-3.
Cannon RA, Stadalnik RC. Postprandial gastric motility in infants with gastroesophageal reflux and delayed gastric emptying. J Nucl Med. 1993;34(12):2120-3.
Cannon, R. A., & Stadalnik, R. C. (1993). Postprandial gastric motility in infants with gastroesophageal reflux and delayed gastric emptying. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine, 34(12), 2120-3.
Cannon RA, Stadalnik RC. Postprandial Gastric Motility in Infants With Gastroesophageal Reflux and Delayed Gastric Emptying. J Nucl Med. 1993;34(12):2120-3. PubMed PMID: 8254398.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Postprandial gastric motility in infants with gastroesophageal reflux and delayed gastric emptying. AU - Cannon,R A, AU - Stadalnik,R C, PY - 1993/12/1/pubmed PY - 1993/12/1/medline PY - 1993/12/1/entrez SP - 2120 EP - 3 JF - Journal of nuclear medicine : official publication, Society of Nuclear Medicine JO - J. Nucl. Med. VL - 34 IS - 12 N2 - Delayed gastric emptying of formula is observed in many infants with gastroesophageal reflux but the mechanisms responsible for this observation are not defined. Postprandial gastric motility was quantified using a perfused catheter placed into the distal stomach of five infants with gastroesophageal reflux and delayed gastric emptying of 99mTc-sulfur colloid-labeled formula. Five infants with reflux who exhibited normal emptying of formula served as the controls. Gastric motility indices were calculated for 60 min following a meal. Half the patients in each group were given metoclopramide following a 30-min recording period. In both groups, postprandial gastric motility was similar and characterized by minimal gastric contractions. Metoclopramide resulted in increased amplitude and duration of antral contractions, but no significant differences were noted between groups. The findings suggest that minimal delays in gastric emptying in infants with gastroesophageal reflux are not associated with significant alterations of postprandial gastric motility. SN - 0161-5505 UR - https://www.unboundmedicine.com/medline/citation/8254398/Postprandial_gastric_motility_in_infants_with_gastroesophageal_reflux_and_delayed_gastric_emptying_ L2 - http://jnm.snmjournals.org/cgi/pmidlookup?view=long&pmid=8254398 DB - PRIME DP - Unbound Medicine ER -