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Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple sclerosis.
Neurology 1993; 43(12):2632-7Neur

Abstract

We performed MRI of brain and spinal cord on 80 patients with multiple sclerosis (MS). Using multi-array coils and fast spin echo, 139 intrinsic lesions were identified in 59 patients (74%). Lesions were more common in the cervical than in the thoracic cord. Cross-sectional areas of the cord, measured from axial images at four levels, showed atrophy in 40%. Clinical disability correlated with cord atrophy but not with cord lesion load. These results show that the use of multi-array coils and fast spin echo allows rapid and sensitive detection of spinal cord lesions in MS and that the cord is involved in the majority of patients. A lack of association between cord lesions and disability may relate to limitations in MR resolution but also suggests that the mechanisms of disability in MS are complex and multifactorial.

Authors+Show Affiliations

Institute of Neurology, National Hospital, London, United Kingdom.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8255468

Citation

Kidd, D, et al. "Spinal Cord MRI Using Multi-array Coils and Fast Spin Echo. II. Findings in Multiple Sclerosis." Neurology, vol. 43, no. 12, 1993, pp. 2632-7.
Kidd D, Thorpe JW, Thompson AJ, et al. Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple sclerosis. Neurology. 1993;43(12):2632-7.
Kidd, D., Thorpe, J. W., Thompson, A. J., Kendall, B. E., Moseley, I. F., MacManus, D. G., ... Miller, D. H. (1993). Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple sclerosis. Neurology, 43(12), pp. 2632-7.
Kidd D, et al. Spinal Cord MRI Using Multi-array Coils and Fast Spin Echo. II. Findings in Multiple Sclerosis. Neurology. 1993;43(12):2632-7. PubMed PMID: 8255468.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple sclerosis. AU - Kidd,D, AU - Thorpe,J W, AU - Thompson,A J, AU - Kendall,B E, AU - Moseley,I F, AU - MacManus,D G, AU - McDonald,W I, AU - Miller,D H, PY - 1993/12/1/pubmed PY - 1993/12/1/medline PY - 1993/12/1/entrez SP - 2632 EP - 7 JF - Neurology JO - Neurology VL - 43 IS - 12 N2 - We performed MRI of brain and spinal cord on 80 patients with multiple sclerosis (MS). Using multi-array coils and fast spin echo, 139 intrinsic lesions were identified in 59 patients (74%). Lesions were more common in the cervical than in the thoracic cord. Cross-sectional areas of the cord, measured from axial images at four levels, showed atrophy in 40%. Clinical disability correlated with cord atrophy but not with cord lesion load. These results show that the use of multi-array coils and fast spin echo allows rapid and sensitive detection of spinal cord lesions in MS and that the cord is involved in the majority of patients. A lack of association between cord lesions and disability may relate to limitations in MR resolution but also suggests that the mechanisms of disability in MS are complex and multifactorial. SN - 0028-3878 UR - https://www.unboundmedicine.com/medline/citation/8255468/full_citation L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=8255468.ui DB - PRIME DP - Unbound Medicine ER -