Tags

Type your tag names separated by a space and hit enter

Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple sclerosis.

Abstract

We performed MRI of brain and spinal cord on 80 patients with multiple sclerosis (MS). Using multi-array coils and fast spin echo, 139 intrinsic lesions were identified in 59 patients (74%). Lesions were more common in the cervical than in the thoracic cord. Cross-sectional areas of the cord, measured from axial images at four levels, showed atrophy in 40%. Clinical disability correlated with cord atrophy but not with cord lesion load. These results show that the use of multi-array coils and fast spin echo allows rapid and sensitive detection of spinal cord lesions in MS and that the cord is involved in the majority of patients. A lack of association between cord lesions and disability may relate to limitations in MR resolution but also suggests that the mechanisms of disability in MS are complex and multifactorial.

Links

  • Aggregator Full Text
  • Authors+Show Affiliations

    ,

    Institute of Neurology, National Hospital, London, United Kingdom.

    , , , , , ,

    Source

    Neurology 43:12 1993 Dec pg 2632-7

    MeSH

    Adult
    Brain
    Humans
    Magnetic Resonance Imaging
    Multiple Sclerosis
    Neck
    Recurrence
    Spinal Cord
    Thorax

    Pub Type(s)

    Journal Article
    Research Support, Non-U.S. Gov't

    Language

    eng

    PubMed ID

    8255468

    Citation

    Kidd, D, et al. "Spinal Cord MRI Using Multi-array Coils and Fast Spin Echo. II. Findings in Multiple Sclerosis." Neurology, vol. 43, no. 12, 1993, pp. 2632-7.
    Kidd D, Thorpe JW, Thompson AJ, et al. Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple sclerosis. Neurology. 1993;43(12):2632-7.
    Kidd, D., Thorpe, J. W., Thompson, A. J., Kendall, B. E., Moseley, I. F., MacManus, D. G., ... Miller, D. H. (1993). Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple sclerosis. Neurology, 43(12), pp. 2632-7.
    Kidd D, et al. Spinal Cord MRI Using Multi-array Coils and Fast Spin Echo. II. Findings in Multiple Sclerosis. Neurology. 1993;43(12):2632-7. PubMed PMID: 8255468.
    * Article titles in AMA citation format should be in sentence-case
    TY - JOUR T1 - Spinal cord MRI using multi-array coils and fast spin echo. II. Findings in multiple sclerosis. AU - Kidd,D, AU - Thorpe,J W, AU - Thompson,A J, AU - Kendall,B E, AU - Moseley,I F, AU - MacManus,D G, AU - McDonald,W I, AU - Miller,D H, PY - 1993/12/1/pubmed PY - 1993/12/1/medline PY - 1993/12/1/entrez SP - 2632 EP - 7 JF - Neurology JO - Neurology VL - 43 IS - 12 N2 - We performed MRI of brain and spinal cord on 80 patients with multiple sclerosis (MS). Using multi-array coils and fast spin echo, 139 intrinsic lesions were identified in 59 patients (74%). Lesions were more common in the cervical than in the thoracic cord. Cross-sectional areas of the cord, measured from axial images at four levels, showed atrophy in 40%. Clinical disability correlated with cord atrophy but not with cord lesion load. These results show that the use of multi-array coils and fast spin echo allows rapid and sensitive detection of spinal cord lesions in MS and that the cord is involved in the majority of patients. A lack of association between cord lesions and disability may relate to limitations in MR resolution but also suggests that the mechanisms of disability in MS are complex and multifactorial. SN - 0028-3878 UR - https://www.unboundmedicine.com/medline/citation/8255468/full_citation L2 - http://ovidsp.ovid.com/ovidweb.cgi?T=JS&PAGE=linkout&SEARCH=8255468.ui DB - PRIME DP - Unbound Medicine ER -