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Assessment of hypoxemia in patients with sleep disorders using saturation impairment time.
Am Rev Respir Dis. 1993 Dec; 148(6 Pt 1):1592-8.AR

Abstract

A method of recording cumulative nocturnal oxygen desaturation was utilized to develop a quantitative index of nocturnal hypoxemia (SIT index) to provide reference values and distributional properties for apneic and nonapneic sleep-disordered patients. The SIT indices were compared in patients with varying degrees of obstructive sleep apnea (OSA) as determined by traditional methods of counting apneas and hypopneas. We studied 298 patients who were divided into five groups based on the presence and frequency of apnea or sleep-related respiratory deterioration. SIT indices for patient groups and individual patients were compared with the respiratory disturbance index (apneas + hypopneas x 60/total sleep time = RDI) using scatter plots, Kruskal-Wallis analysis of variance, and Mann-Whitney U tests. The OSA and non-respiratory-impaired patient groups had mean SIT values that were significantly different (p < 0.05). Subjects with severe apnea differed (p < 0.05) from subjects with mild and moderate apnea at SIT index thresholds < baseline, < 90, < 80, and < 70% SaO2, but subjects with mild and moderate apnea did not differ statistically from each other at any threshold. In individual patients with similar RDI values, considerable variation in SIT index can be seen, and the reverse is also true. This suggests that using both RDI and SIT may provide complementary information in assessing the severity of OSA.

Authors+Show Affiliations

Department of Neurology, Louisiana State University, Shreveport.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8256907

Citation

Chesson, A L., et al. "Assessment of Hypoxemia in Patients With Sleep Disorders Using Saturation Impairment Time." The American Review of Respiratory Disease, vol. 148, no. 6 Pt 1, 1993, pp. 1592-8.
Chesson AL, Anderson WM, Walls RC, et al. Assessment of hypoxemia in patients with sleep disorders using saturation impairment time. Am Rev Respir Dis. 1993;148(6 Pt 1):1592-8.
Chesson, A. L., Anderson, W. M., Walls, R. C., & Bairnsfather, L. E. (1993). Assessment of hypoxemia in patients with sleep disorders using saturation impairment time. The American Review of Respiratory Disease, 148(6 Pt 1), 1592-8.
Chesson AL, et al. Assessment of Hypoxemia in Patients With Sleep Disorders Using Saturation Impairment Time. Am Rev Respir Dis. 1993;148(6 Pt 1):1592-8. PubMed PMID: 8256907.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Assessment of hypoxemia in patients with sleep disorders using saturation impairment time. AU - Chesson,A L,Jr AU - Anderson,W M, AU - Walls,R C, AU - Bairnsfather,L E, PY - 1993/12/1/pubmed PY - 2001/3/28/medline PY - 1993/12/1/entrez SP - 1592 EP - 8 JF - The American review of respiratory disease JO - Am Rev Respir Dis VL - 148 IS - 6 Pt 1 N2 - A method of recording cumulative nocturnal oxygen desaturation was utilized to develop a quantitative index of nocturnal hypoxemia (SIT index) to provide reference values and distributional properties for apneic and nonapneic sleep-disordered patients. The SIT indices were compared in patients with varying degrees of obstructive sleep apnea (OSA) as determined by traditional methods of counting apneas and hypopneas. We studied 298 patients who were divided into five groups based on the presence and frequency of apnea or sleep-related respiratory deterioration. SIT indices for patient groups and individual patients were compared with the respiratory disturbance index (apneas + hypopneas x 60/total sleep time = RDI) using scatter plots, Kruskal-Wallis analysis of variance, and Mann-Whitney U tests. The OSA and non-respiratory-impaired patient groups had mean SIT values that were significantly different (p < 0.05). Subjects with severe apnea differed (p < 0.05) from subjects with mild and moderate apnea at SIT index thresholds < baseline, < 90, < 80, and < 70% SaO2, but subjects with mild and moderate apnea did not differ statistically from each other at any threshold. In individual patients with similar RDI values, considerable variation in SIT index can be seen, and the reverse is also true. This suggests that using both RDI and SIT may provide complementary information in assessing the severity of OSA. SN - 0003-0805 UR - https://www.unboundmedicine.com/medline/citation/8256907/Assessment_of_hypoxemia_in_patients_with_sleep_disorders_using_saturation_impairment_time. L2 - https://www.atsjournals.org/doi/10.1164/ajrccm/148.6_Pt_1.1592?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -