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Does a vegetarian diet control Wilson's disease?
J Am Coll Nutr. 1993 Oct; 12(5):527-30.JA

Abstract

The literature indicates that copper (Cu) is less bioavailable from a vegetarian as compared to mixed diet. Further, several groups, including ours, find rather marginal average Cu intake in the typical American diet. For example, our data indicate that Wilson's disease patients on a typical American diet ingest only about 25% more Cu than is required. This suggests that a vegetarian diet, if it reduced bioavailability by about 25% or more, would be an adequate maintenance therapy for Wilson's disease. Observations in two of our patients, who were on lactovegetarian diets by choice, and who were almost totally noncompliant with anti-Cu therapy, support this view. These observations suggest that vegetarian diets may be a management tool for Wilson's disease. They also further emphasize the marginal Cu intake in American diets, and suggest that some seemingly healthy people, particularly vegetarians, may be at risk for mild Cu deficiency.

Authors+Show Affiliations

Department of Human Genetics, University of Michigan Medical School, Ann Arbor 48109-0618.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Case Reports
Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

8263268

Citation

Brewer, G J., et al. "Does a Vegetarian Diet Control Wilson's Disease?" Journal of the American College of Nutrition, vol. 12, no. 5, 1993, pp. 527-30.
Brewer GJ, Yuzbasiyan-Gurkan V, Dick R, et al. Does a vegetarian diet control Wilson's disease? J Am Coll Nutr. 1993;12(5):527-30.
Brewer, G. J., Yuzbasiyan-Gurkan, V., Dick, R., Wang, Y., & Johnson, V. (1993). Does a vegetarian diet control Wilson's disease? Journal of the American College of Nutrition, 12(5), 527-30.
Brewer GJ, et al. Does a Vegetarian Diet Control Wilson's Disease. J Am Coll Nutr. 1993;12(5):527-30. PubMed PMID: 8263268.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Does a vegetarian diet control Wilson's disease? AU - Brewer,G J, AU - Yuzbasiyan-Gurkan,V, AU - Dick,R, AU - Wang,Y, AU - Johnson,V, PY - 1993/10/1/pubmed PY - 1993/10/1/medline PY - 1993/10/1/entrez SP - 527 EP - 30 JF - Journal of the American College of Nutrition JO - J Am Coll Nutr VL - 12 IS - 5 N2 - The literature indicates that copper (Cu) is less bioavailable from a vegetarian as compared to mixed diet. Further, several groups, including ours, find rather marginal average Cu intake in the typical American diet. For example, our data indicate that Wilson's disease patients on a typical American diet ingest only about 25% more Cu than is required. This suggests that a vegetarian diet, if it reduced bioavailability by about 25% or more, would be an adequate maintenance therapy for Wilson's disease. Observations in two of our patients, who were on lactovegetarian diets by choice, and who were almost totally noncompliant with anti-Cu therapy, support this view. These observations suggest that vegetarian diets may be a management tool for Wilson's disease. They also further emphasize the marginal Cu intake in American diets, and suggest that some seemingly healthy people, particularly vegetarians, may be at risk for mild Cu deficiency. SN - 0731-5724 UR - https://www.unboundmedicine.com/medline/citation/8263268/Does_a_vegetarian_diet_control_Wilson's_disease L2 - http://www.tandfonline.com/doi/full/10.1080/07315724.1993.10718347 DB - PRIME DP - Unbound Medicine ER -