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Acquired risk factors for deep-vein thrombosis in symptomatic outpatients.
Arch Intern Med. 1994 Jan 24; 154(2):164-8.AI

Abstract

BACKGROUND

Epidemiologic studies on deep-vein thrombosis (DVT) have been mainly confined to the inpatient population. The aim of this study was to investigate the association between DVT and acquired risk factors in a large cohort of outpatients with clinically suspected DVT.

METHODS

Consecutive outpatients with clinically suspected DVT were enrolled in the study. Before objective testing, all patients were interviewed by a trained physician for the presence of risk factors for DVT development. Subsequently, the presence or absence of DVT was assessed with venography.

RESULTS

Approximately 50% of cases of DVT were considered to be secondary to a major risk factor (immobilization, trauma, and/or recent surgery). Among additional risk factors, only increased age (over 60 years), male gender, malignant neoplasm, heart failure, systemic lupus erythematosus, and arteriopathy were independently associated with the risk of acute DVT.

CONCLUSION

Major risk factors for venous thromboembolism are a common cause of DVT among symptomatic outpatients; therefore, the usefulness of extending DVT prophylaxis in the outpatient setting should be tested. The role of additional risk factors in the development of DVT needs to be established by properly designed studies.

Authors+Show Affiliations

Department of Pathologic Medicine II, University of Padua, Italy.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8285811

Citation

Cogo, A, et al. "Acquired Risk Factors for Deep-vein Thrombosis in Symptomatic Outpatients." Archives of Internal Medicine, vol. 154, no. 2, 1994, pp. 164-8.
Cogo A, Bernardi E, Prandoni P, et al. Acquired risk factors for deep-vein thrombosis in symptomatic outpatients. Arch Intern Med. 1994;154(2):164-8.
Cogo, A., Bernardi, E., Prandoni, P., Girolami, B., Noventa, F., Simioni, P., & Girolami, A. (1994). Acquired risk factors for deep-vein thrombosis in symptomatic outpatients. Archives of Internal Medicine, 154(2), 164-8.
Cogo A, et al. Acquired Risk Factors for Deep-vein Thrombosis in Symptomatic Outpatients. Arch Intern Med. 1994 Jan 24;154(2):164-8. PubMed PMID: 8285811.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Acquired risk factors for deep-vein thrombosis in symptomatic outpatients. AU - Cogo,A, AU - Bernardi,E, AU - Prandoni,P, AU - Girolami,B, AU - Noventa,F, AU - Simioni,P, AU - Girolami,A, PY - 1994/1/24/pubmed PY - 1994/1/24/medline PY - 1994/1/24/entrez SP - 164 EP - 8 JF - Archives of internal medicine JO - Arch Intern Med VL - 154 IS - 2 N2 - BACKGROUND: Epidemiologic studies on deep-vein thrombosis (DVT) have been mainly confined to the inpatient population. The aim of this study was to investigate the association between DVT and acquired risk factors in a large cohort of outpatients with clinically suspected DVT. METHODS: Consecutive outpatients with clinically suspected DVT were enrolled in the study. Before objective testing, all patients were interviewed by a trained physician for the presence of risk factors for DVT development. Subsequently, the presence or absence of DVT was assessed with venography. RESULTS: Approximately 50% of cases of DVT were considered to be secondary to a major risk factor (immobilization, trauma, and/or recent surgery). Among additional risk factors, only increased age (over 60 years), male gender, malignant neoplasm, heart failure, systemic lupus erythematosus, and arteriopathy were independently associated with the risk of acute DVT. CONCLUSION: Major risk factors for venous thromboembolism are a common cause of DVT among symptomatic outpatients; therefore, the usefulness of extending DVT prophylaxis in the outpatient setting should be tested. The role of additional risk factors in the development of DVT needs to be established by properly designed studies. SN - 0003-9926 UR - https://www.unboundmedicine.com/medline/citation/8285811/Acquired_risk_factors_for_deep_vein_thrombosis_in_symptomatic_outpatients_ L2 - https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/vol/154/pg/164 DB - PRIME DP - Unbound Medicine ER -