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Fat high in stearic acid favorably affects blood lipids and factor VII coagulant activity in comparison with fats high in palmitic acid or high in myristic and lauric acids.
Am J Clin Nutr 1994; 59(2):371-7AJ

Abstract

The effect of fats high in individual, prevalent saturated dietary fatty acids on lipoproteins and hemostatic variables in young healthy subjects was evaluated in a randomized strictly controlled metabolic feeding study. Three experimental diets: shea butter (S; 42% stearic acid), palm oil (P; 43% palmitic palmitic acid), and palm-kernel oil with high-oleic sunflower oil (ML; 10% myristic acid, 30% lauric acid) were served to 15 men for 3 wk each, separated by washout periods. Diet S compared with diet P resulted in significant reduction in plasma cholesterol (22%) LDL cholesterol (26%), apolipoprotein B (18%), HDL cholesterol (12%), apolipoprotein A-I (13%), and a 13% lower factor VII coagulant activity (P = 0.001). Similar differences were observed between diets S and ML. In conclusion, intake of shea butter high in stearic acid favorably affects blood lipids and factor VII coagulant activity in young men, compared with fats high in saturated fatty acids with 12-16 carbons.

Authors+Show Affiliations

Research Department of Human Nutrition, Royal Veterinary and Agricultural University, Copenhagen, Denmark.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

8310987

Citation

Tholstrup, T, et al. "Fat High in Stearic Acid Favorably Affects Blood Lipids and Factor VII Coagulant Activity in Comparison With Fats High in Palmitic Acid or High in Myristic and Lauric Acids." The American Journal of Clinical Nutrition, vol. 59, no. 2, 1994, pp. 371-7.
Tholstrup T, Marckmann P, Jespersen J, et al. Fat high in stearic acid favorably affects blood lipids and factor VII coagulant activity in comparison with fats high in palmitic acid or high in myristic and lauric acids. Am J Clin Nutr. 1994;59(2):371-7.
Tholstrup, T., Marckmann, P., Jespersen, J., & Sandström, B. (1994). Fat high in stearic acid favorably affects blood lipids and factor VII coagulant activity in comparison with fats high in palmitic acid or high in myristic and lauric acids. The American Journal of Clinical Nutrition, 59(2), pp. 371-7.
Tholstrup T, et al. Fat High in Stearic Acid Favorably Affects Blood Lipids and Factor VII Coagulant Activity in Comparison With Fats High in Palmitic Acid or High in Myristic and Lauric Acids. Am J Clin Nutr. 1994;59(2):371-7. PubMed PMID: 8310987.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Fat high in stearic acid favorably affects blood lipids and factor VII coagulant activity in comparison with fats high in palmitic acid or high in myristic and lauric acids. AU - Tholstrup,T, AU - Marckmann,P, AU - Jespersen,J, AU - Sandström,B, PY - 1994/2/1/pubmed PY - 1994/2/1/medline PY - 1994/2/1/entrez SP - 371 EP - 7 JF - The American journal of clinical nutrition JO - Am. J. Clin. Nutr. VL - 59 IS - 2 N2 - The effect of fats high in individual, prevalent saturated dietary fatty acids on lipoproteins and hemostatic variables in young healthy subjects was evaluated in a randomized strictly controlled metabolic feeding study. Three experimental diets: shea butter (S; 42% stearic acid), palm oil (P; 43% palmitic palmitic acid), and palm-kernel oil with high-oleic sunflower oil (ML; 10% myristic acid, 30% lauric acid) were served to 15 men for 3 wk each, separated by washout periods. Diet S compared with diet P resulted in significant reduction in plasma cholesterol (22%) LDL cholesterol (26%), apolipoprotein B (18%), HDL cholesterol (12%), apolipoprotein A-I (13%), and a 13% lower factor VII coagulant activity (P = 0.001). Similar differences were observed between diets S and ML. In conclusion, intake of shea butter high in stearic acid favorably affects blood lipids and factor VII coagulant activity in young men, compared with fats high in saturated fatty acids with 12-16 carbons. SN - 0002-9165 UR - https://www.unboundmedicine.com/medline/citation/8310987/Fat_high_in_stearic_acid_favorably_affects_blood_lipids_and_factor_VII_coagulant_activity_in_comparison_with_fats_high_in_palmitic_acid_or_high_in_myristic_and_lauric_acids_ L2 - https://academic.oup.com/ajcn/article-lookup/doi/10.1093/ajcn/59.2.371 DB - PRIME DP - Unbound Medicine ER -