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Viral hepatitis in Bucharest.
Bull World Health Organ. 1993; 71(6):781-6.BW

Abstract

A seroprevalence survey of viral hepatitis was conducted in Bucharest, Romania, between April and July 1990 on a systematic sample of 1355 persons drawn from the general population and groups at higher risk of infection. Sera were tested for hepatitis A, B, and C (HAV, HBV and HCV, resp.) markers using an enzyme-linked immunosorbent assay (ELISA) method. The prevalences of HAV and HBV markers were high in all groups. A total of 47% of the adults from the general population and 39.8% of the children aged 0-16 years had at least one HBV marker. Of the pregnant women 7.8% were positive for hepatitis B surface antigen. Among infants (0-3 years of age) living in orphanages, the prevalence of at least one HBV marker was 54.6%. The findings also confirmed that HCV was circulating in Romania. The results are consistent with national surveillance data and confirm that viral hepatitis is a major public health problem in Romania. Preventive measures will have to include HBV immunization of infants, with an appropriately targeted immunization strategy being determined through further epidemiological studies.

Authors+Show Affiliations

Laboratory of Viral Hepatitis, Stefan Nicolau Institute of Virology, Bucharest, Romania.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8313496

Citation

Paquet, C, et al. "Viral Hepatitis in Bucharest." Bulletin of the World Health Organization, vol. 71, no. 6, 1993, pp. 781-6.
Paquet C, Babes VT, Drucker J, et al. Viral hepatitis in Bucharest. Bull World Health Organ. 1993;71(6):781-6.
Paquet, C., Babes, V. T., Drucker, J., Sénémaud, B., & Dobrescu, A. (1993). Viral hepatitis in Bucharest. Bulletin of the World Health Organization, 71(6), 781-6.
Paquet C, et al. Viral Hepatitis in Bucharest. Bull World Health Organ. 1993;71(6):781-6. PubMed PMID: 8313496.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Viral hepatitis in Bucharest. AU - Paquet,C, AU - Babes,V T, AU - Drucker,J, AU - Sénémaud,B, AU - Dobrescu,A, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez KW - Adult KW - Age Factors KW - Child KW - Demographic Factors KW - Developed Countries KW - Diseases KW - Eastern Europe KW - Europe KW - Examinations And Diagnoses KW - Hematologic Tests KW - Hepatitis KW - Laboratory Examinations And Diagnoses KW - Laboratory Procedures KW - Population KW - Population Characteristics KW - Research Report KW - Romania KW - Urban Population KW - Viral Diseases KW - Youth SP - 781 EP - 6 JF - Bulletin of the World Health Organization JO - Bull World Health Organ VL - 71 IS - 6 N2 - A seroprevalence survey of viral hepatitis was conducted in Bucharest, Romania, between April and July 1990 on a systematic sample of 1355 persons drawn from the general population and groups at higher risk of infection. Sera were tested for hepatitis A, B, and C (HAV, HBV and HCV, resp.) markers using an enzyme-linked immunosorbent assay (ELISA) method. The prevalences of HAV and HBV markers were high in all groups. A total of 47% of the adults from the general population and 39.8% of the children aged 0-16 years had at least one HBV marker. Of the pregnant women 7.8% were positive for hepatitis B surface antigen. Among infants (0-3 years of age) living in orphanages, the prevalence of at least one HBV marker was 54.6%. The findings also confirmed that HCV was circulating in Romania. The results are consistent with national surveillance data and confirm that viral hepatitis is a major public health problem in Romania. Preventive measures will have to include HBV immunization of infants, with an appropriately targeted immunization strategy being determined through further epidemiological studies. SN - 0042-9686 UR - https://www.unboundmedicine.com/medline/citation/8313496/Viral_hepatitis_in_Bucharest_ L2 - https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/8313496/ DB - PRIME DP - Unbound Medicine ER -