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Oolong tea polyphenols inhibit experimental dental caries in SPF rats infected with mutans streptococci.
Caries Res 1993; 27(2):124-9CR

Abstract

An extract of oolong tea (semifermented tea leaves of Camellia sinensis) and its chromatographically isolated polyphenolic compound was examined for in vitro inhibitory effects on glucosyltransferases (GTases) of mutans streptococci and on caries development in Sprague-Dawley rats infected with mutans streptococci. The samples showed no detectable effect on the growth of mutans streptococci. However, insoluble glucan synthesis from sucrose by the GTases of Streptococcus mutans MT8148R and Streptococcus sobrinus 6715 was markedly inhibited, as was sucrose-dependent cell adherence of these mutans streptococci. The administration of the oolong tea extract and the isolated polyphenol compound into diet 2000 and drinking water resulted in significant reductions in caries development and plaque accumulation in the rats infected with mutans streptococci. The active components in the oolong tea extract were presumptively identified as polymeric polyphenols which were specific for oolong tea leaves. These results indicate that the oolong tea polyphenolic compounds could be useful for controlling dental caries.

Authors+Show Affiliations

Department of Pedodontics, Osaka University, Faculty of Dentistry, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8319255

Citation

Ooshima, T, et al. "Oolong Tea Polyphenols Inhibit Experimental Dental Caries in SPF Rats Infected With Mutans Streptococci." Caries Research, vol. 27, no. 2, 1993, pp. 124-9.
Ooshima T, Minami T, Aono W, et al. Oolong tea polyphenols inhibit experimental dental caries in SPF rats infected with mutans streptococci. Caries Res. 1993;27(2):124-9.
Ooshima, T., Minami, T., Aono, W., Izumitani, A., Sobue, S., Fujiwara, T., ... Hamada, S. (1993). Oolong tea polyphenols inhibit experimental dental caries in SPF rats infected with mutans streptococci. Caries Research, 27(2), pp. 124-9.
Ooshima T, et al. Oolong Tea Polyphenols Inhibit Experimental Dental Caries in SPF Rats Infected With Mutans Streptococci. Caries Res. 1993;27(2):124-9. PubMed PMID: 8319255.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Oolong tea polyphenols inhibit experimental dental caries in SPF rats infected with mutans streptococci. AU - Ooshima,T, AU - Minami,T, AU - Aono,W, AU - Izumitani,A, AU - Sobue,S, AU - Fujiwara,T, AU - Kawabata,S, AU - Hamada,S, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez SP - 124 EP - 9 JF - Caries research JO - Caries Res. VL - 27 IS - 2 N2 - An extract of oolong tea (semifermented tea leaves of Camellia sinensis) and its chromatographically isolated polyphenolic compound was examined for in vitro inhibitory effects on glucosyltransferases (GTases) of mutans streptococci and on caries development in Sprague-Dawley rats infected with mutans streptococci. The samples showed no detectable effect on the growth of mutans streptococci. However, insoluble glucan synthesis from sucrose by the GTases of Streptococcus mutans MT8148R and Streptococcus sobrinus 6715 was markedly inhibited, as was sucrose-dependent cell adherence of these mutans streptococci. The administration of the oolong tea extract and the isolated polyphenol compound into diet 2000 and drinking water resulted in significant reductions in caries development and plaque accumulation in the rats infected with mutans streptococci. The active components in the oolong tea extract were presumptively identified as polymeric polyphenols which were specific for oolong tea leaves. These results indicate that the oolong tea polyphenolic compounds could be useful for controlling dental caries. SN - 0008-6568 UR - https://www.unboundmedicine.com/medline/citation/8319255/Oolong_tea_polyphenols_inhibit_experimental_dental_caries_in_SPF_rats_infected_with_mutans_streptococci_ L2 - https://www.karger.com?DOI=10.1159/000261529 DB - PRIME DP - Unbound Medicine ER -