Tags

Type your tag names separated by a space and hit enter

Prophylactic endoscopic sclerotherapy of esophageal varices in liver cirrhosis--long-term follow-up and final results of a multicenter prospective controlled randomized trial in Vienna.
Endoscopy. 1993 May; 25(4):287-9.E

Abstract

This study reports the final results of a randomized multicenter trial on prophylactic endoscopic sclerotherapy of large esophageal varices in patients with liver cirrhosis. Forty-one patients received prophylactic treatment and 41 patients were in the control group. A first analysis 3 years after beginning the study revealed no significant difference in the distribution of the bleeding free intervals between both groups, but indicated a tendency towards longer survival of patients with prophylactic sclerotherapy. The follow-up of patients was continued for an additional 3 years. After this time, 53.7% of patients in the sclerotherapy group and 39.1% of patients in the control group were still alive. During the study period of 6 years, variceal bleeding was observed in 31.7% of patients in the sclerotherapy group and in 36.6% of patients in the control group. Neither survival nor incidence of bleeding were statistically different between the two groups. The etiology of cirrhosis did not influence the survival.

Authors+Show Affiliations

Department of Gastroenterology and Hepatology, University of Vienna, Austria.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Multicenter Study
Randomized Controlled Trial

Language

eng

PubMed ID

8330548

Citation

Pötzi, R, et al. "Prophylactic Endoscopic Sclerotherapy of Esophageal Varices in Liver Cirrhosis--long-term Follow-up and Final Results of a Multicenter Prospective Controlled Randomized Trial in Vienna." Endoscopy, vol. 25, no. 4, 1993, pp. 287-9.
Pötzi R, Bauer P, Schöfl R, et al. Prophylactic endoscopic sclerotherapy of esophageal varices in liver cirrhosis--long-term follow-up and final results of a multicenter prospective controlled randomized trial in Vienna. Endoscopy. 1993;25(4):287-9.
Pötzi, R., Bauer, P., Schöfl, R., Reichel, W., Kerstan, E., Renner, F., & Gangl, A. (1993). Prophylactic endoscopic sclerotherapy of esophageal varices in liver cirrhosis--long-term follow-up and final results of a multicenter prospective controlled randomized trial in Vienna. Endoscopy, 25(4), 287-9.
Pötzi R, et al. Prophylactic Endoscopic Sclerotherapy of Esophageal Varices in Liver Cirrhosis--long-term Follow-up and Final Results of a Multicenter Prospective Controlled Randomized Trial in Vienna. Endoscopy. 1993;25(4):287-9. PubMed PMID: 8330548.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Prophylactic endoscopic sclerotherapy of esophageal varices in liver cirrhosis--long-term follow-up and final results of a multicenter prospective controlled randomized trial in Vienna. AU - Pötzi,R, AU - Bauer,P, AU - Schöfl,R, AU - Reichel,W, AU - Kerstan,E, AU - Renner,F, AU - Gangl,A, PY - 1993/5/1/pubmed PY - 1993/5/1/medline PY - 1993/5/1/entrez SP - 287 EP - 9 JF - Endoscopy JO - Endoscopy VL - 25 IS - 4 N2 - This study reports the final results of a randomized multicenter trial on prophylactic endoscopic sclerotherapy of large esophageal varices in patients with liver cirrhosis. Forty-one patients received prophylactic treatment and 41 patients were in the control group. A first analysis 3 years after beginning the study revealed no significant difference in the distribution of the bleeding free intervals between both groups, but indicated a tendency towards longer survival of patients with prophylactic sclerotherapy. The follow-up of patients was continued for an additional 3 years. After this time, 53.7% of patients in the sclerotherapy group and 39.1% of patients in the control group were still alive. During the study period of 6 years, variceal bleeding was observed in 31.7% of patients in the sclerotherapy group and in 36.6% of patients in the control group. Neither survival nor incidence of bleeding were statistically different between the two groups. The etiology of cirrhosis did not influence the survival. SN - 0013-726X UR - https://www.unboundmedicine.com/medline/citation/8330548/Prophylactic_endoscopic_sclerotherapy_of_esophageal_varices_in_liver_cirrhosis__long_term_follow_up_and_final_results_of_a_multicenter_prospective_controlled_randomized_trial_in_Vienna_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2007-1010316 DB - PRIME DP - Unbound Medicine ER -