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New approaches for the treatment of bacterial vaginosis.
Am J Obstet Gynecol. 1993 Aug; 169(2 Pt 2):479-82.AJ

Abstract

OBJECTIVE

Review alternative approaches to oral metronidazole for the treatment of bacterial vaginosis.

STUDY DESIGN

Assessment of clinical trials on the treatment of bacterial vaginosis with regimens other than 5 to 7 days of metronidazole.

RESULTS

Single-dose metronidazole, 2 gm orally, is as effective as 5- to 7-day courses of oral metronidazole, with cure rates in the 80% to 90% range. Oral clindamycin results in more than a 90% clinical cure rate. Intravaginal clindamycin cream 2% and intravaginal metronidazole gel 0.75% are associated with clinical cure rates similar to those for oral metronidazole.

CONCLUSIONS

Single-dose metronidazole, oral clindamycin, intravaginal clindamycin cream, and intravaginal metronidazole gel are effective and safe alternatives to a 5- to 7-day course of oral metronidazole for the treatment of bacterial vaginosis.

Authors+Show Affiliations

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Pittsburgh Magee-Womens Hospital, PA 15213.

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

8357050

Citation

Sweet, R L.. "New Approaches for the Treatment of Bacterial Vaginosis." American Journal of Obstetrics and Gynecology, vol. 169, no. 2 Pt 2, 1993, pp. 479-82.
Sweet RL. New approaches for the treatment of bacterial vaginosis. Am J Obstet Gynecol. 1993;169(2 Pt 2):479-82.
Sweet, R. L. (1993). New approaches for the treatment of bacterial vaginosis. American Journal of Obstetrics and Gynecology, 169(2 Pt 2), 479-82.
Sweet RL. New Approaches for the Treatment of Bacterial Vaginosis. Am J Obstet Gynecol. 1993;169(2 Pt 2):479-82. PubMed PMID: 8357050.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New approaches for the treatment of bacterial vaginosis. A1 - Sweet,R L, PY - 1993/8/1/pubmed PY - 1993/8/1/medline PY - 1993/8/1/entrez SP - 479 EP - 82 JF - American journal of obstetrics and gynecology JO - Am. J. Obstet. Gynecol. VL - 169 IS - 2 Pt 2 N2 - OBJECTIVE: Review alternative approaches to oral metronidazole for the treatment of bacterial vaginosis. STUDY DESIGN: Assessment of clinical trials on the treatment of bacterial vaginosis with regimens other than 5 to 7 days of metronidazole. RESULTS: Single-dose metronidazole, 2 gm orally, is as effective as 5- to 7-day courses of oral metronidazole, with cure rates in the 80% to 90% range. Oral clindamycin results in more than a 90% clinical cure rate. Intravaginal clindamycin cream 2% and intravaginal metronidazole gel 0.75% are associated with clinical cure rates similar to those for oral metronidazole. CONCLUSIONS: Single-dose metronidazole, oral clindamycin, intravaginal clindamycin cream, and intravaginal metronidazole gel are effective and safe alternatives to a 5- to 7-day course of oral metronidazole for the treatment of bacterial vaginosis. SN - 0002-9378 UR - https://www.unboundmedicine.com/medline/citation/8357050/New_approaches_for_the_treatment_of_bacterial_vaginosis_ L2 - https://linkinghub.elsevier.com/retrieve/pii/0002-9378(93)90346-K DB - PRIME DP - Unbound Medicine ER -