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Endoscopic diagnosis and resection treatment for flat adenoma with severe dysplasia.
Am J Gastroenterol. 1993 Sep; 88(9):1421-3.AJ

Abstract

In a prospective study from 1988 to 1991, we discovered 31 flat colon adenomas in 29 patients and performed endoscopic resection of 27 of these lesions, using the strip biopsy technique. All of these lesions were safely and completely resected even in the thin walls of the colon. All 27 lesions were histologically flat adenomas confined to the mucosa, with a maximum diameter of 3-20 mm. Thirteen were identified as severe dysplasia, three as moderate dysplasia, and 11 as mild dysplasia. These lesions were more clearly defined after they were sprayed with indigo carmine endoscopically. The 13 flat adenomas with severe dysplasia were morphologically slightly depressed red lesions with elevation of the surrounding mucosa (six lesions) and flat round red lesions with no changes in the surrounding mucosa (seven lesions). Due to the high incidence of severe dysplasia found in flat adenomas, removal using strip biopsy is recommended.

Authors+Show Affiliations

Karita M
First Department of Internal Medicine, Yamaguchi University School of Medicine, Japan.
Cantero D
No affiliation info available
Okita K
No affiliation info available

MeSH

AdenomaAgedAged, 80 and overBiopsyColonic NeoplasmsColonoscopyFemaleHumansMaleMiddle AgedProspective Studies

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8362841

Citation

Karita, M, et al. "Endoscopic Diagnosis and Resection Treatment for Flat Adenoma With Severe Dysplasia." The American Journal of Gastroenterology, vol. 88, no. 9, 1993, pp. 1421-3.
Karita M, Cantero D, Okita K. Endoscopic diagnosis and resection treatment for flat adenoma with severe dysplasia. Am J Gastroenterol. 1993;88(9):1421-3.
Karita, M., Cantero, D., & Okita, K. (1993). Endoscopic diagnosis and resection treatment for flat adenoma with severe dysplasia. The American Journal of Gastroenterology, 88(9), 1421-3.
Karita M, Cantero D, Okita K. Endoscopic Diagnosis and Resection Treatment for Flat Adenoma With Severe Dysplasia. Am J Gastroenterol. 1993;88(9):1421-3. PubMed PMID: 8362841.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Endoscopic diagnosis and resection treatment for flat adenoma with severe dysplasia. AU - Karita,M, AU - Cantero,D, AU - Okita,K, PY - 1993/9/1/pubmed PY - 1993/9/1/medline PY - 1993/9/1/entrez SP - 1421 EP - 3 JF - The American journal of gastroenterology JO - Am J Gastroenterol VL - 88 IS - 9 N2 - In a prospective study from 1988 to 1991, we discovered 31 flat colon adenomas in 29 patients and performed endoscopic resection of 27 of these lesions, using the strip biopsy technique. All of these lesions were safely and completely resected even in the thin walls of the colon. All 27 lesions were histologically flat adenomas confined to the mucosa, with a maximum diameter of 3-20 mm. Thirteen were identified as severe dysplasia, three as moderate dysplasia, and 11 as mild dysplasia. These lesions were more clearly defined after they were sprayed with indigo carmine endoscopically. The 13 flat adenomas with severe dysplasia were morphologically slightly depressed red lesions with elevation of the surrounding mucosa (six lesions) and flat round red lesions with no changes in the surrounding mucosa (seven lesions). Due to the high incidence of severe dysplasia found in flat adenomas, removal using strip biopsy is recommended. SN - 0002-9270 UR - https://www.unboundmedicine.com/medline/citation/8362841/Endoscopic_diagnosis_and_resection_treatment_for_flat_adenoma_with_severe_dysplasia_ L2 - https://medlineplus.gov/colonoscopy.html DB - PRIME DP - Unbound Medicine ER -