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[A case of Wernicke-Korsakoff syndrome caused by gastrojejunostomy--specific findings of MRI and SPECT].
Rinsho Shinkeigaku. 1993 May; 33(5):530-4.RS

Abstract

A 63-year-old woman with Wernicke-Korsakoff syndrome, despite the absence of alcoholism and malnutrition, is reported. She had undergone gastrojejunostomy for ileus 30 years ago, and this operation was thought to be an important risk factor for her vitamin B1 deficiency. Brain MRI showed symmetrical high intensity areas on T2-weighted images in the periaqueductal region and bilateral dorsomedial nuclei of the thalamus. On single photon emission computed tomography (SPECT) using 99mTc-hexamethylpropyleneamine oxime, bilateral frontal perfusion was reduced, which was attributed to thalamo-cortical diaschisis due to injury to the dorsomedial nuclei of the thalamus. Presumably this phenomenon explains the Korsakoff psychosis. A history of gastrojejunostomy, even if normal intake is possible, is a risk factor for vitamin B1 deficiency, and should be considered in the differential diagnosis of Wernicke-Korsakoff syndrome.

Authors+Show Affiliations

Okino S
Department of Neurology, School of Medicine, Kanazawa University.
Sakajiri KI
No affiliation info available
Fukushima K
No affiliation info available
Ide Y
No affiliation info available
Takamori M
No affiliation info available

MeSH

Alcohol Amnestic DisorderFemaleGastroenterostomyHumansJejunostomyMagnetic Resonance ImagingMiddle AgedTomography, Emission-Computed, Single-PhotonWernicke Encephalopathy

Pub Type(s)

Case Reports
English Abstract
Journal Article

Language

jpn

PubMed ID

8365060

Citation

Okino, S, et al. "[A Case of Wernicke-Korsakoff Syndrome Caused By Gastrojejunostomy--specific Findings of MRI and SPECT]." Rinsho Shinkeigaku = Clinical Neurology, vol. 33, no. 5, 1993, pp. 530-4.
Okino S, Sakajiri KI, Fukushima K, et al. [A case of Wernicke-Korsakoff syndrome caused by gastrojejunostomy--specific findings of MRI and SPECT]. Rinsho Shinkeigaku. 1993;33(5):530-4.
Okino, S., Sakajiri, K. I., Fukushima, K., Ide, Y., & Takamori, M. (1993). [A case of Wernicke-Korsakoff syndrome caused by gastrojejunostomy--specific findings of MRI and SPECT]. Rinsho Shinkeigaku = Clinical Neurology, 33(5), 530-4.
Okino S, et al. [A Case of Wernicke-Korsakoff Syndrome Caused By Gastrojejunostomy--specific Findings of MRI and SPECT]. Rinsho Shinkeigaku. 1993;33(5):530-4. PubMed PMID: 8365060.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [A case of Wernicke-Korsakoff syndrome caused by gastrojejunostomy--specific findings of MRI and SPECT]. AU - Okino,S, AU - Sakajiri,K I, AU - Fukushima,K, AU - Ide,Y, AU - Takamori,M, PY - 1993/5/1/pubmed PY - 1993/5/1/medline PY - 1993/5/1/entrez SP - 530 EP - 4 JF - Rinsho shinkeigaku = Clinical neurology JO - Rinsho Shinkeigaku VL - 33 IS - 5 N2 - A 63-year-old woman with Wernicke-Korsakoff syndrome, despite the absence of alcoholism and malnutrition, is reported. She had undergone gastrojejunostomy for ileus 30 years ago, and this operation was thought to be an important risk factor for her vitamin B1 deficiency. Brain MRI showed symmetrical high intensity areas on T2-weighted images in the periaqueductal region and bilateral dorsomedial nuclei of the thalamus. On single photon emission computed tomography (SPECT) using 99mTc-hexamethylpropyleneamine oxime, bilateral frontal perfusion was reduced, which was attributed to thalamo-cortical diaschisis due to injury to the dorsomedial nuclei of the thalamus. Presumably this phenomenon explains the Korsakoff psychosis. A history of gastrojejunostomy, even if normal intake is possible, is a risk factor for vitamin B1 deficiency, and should be considered in the differential diagnosis of Wernicke-Korsakoff syndrome. SN - 0009-918X UR - https://www.unboundmedicine.com/medline/citation/8365060/[A_case_of_Wernicke_Korsakoff_syndrome_caused_by_gastrojejunostomy__specific_findings_of_MRI_and_SPECT]_ L2 - https://www.diseaseinfosearch.org/result/7472 DB - PRIME DP - Unbound Medicine ER -