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[Clinical evaluation of the tolerance for a soy-based special milk formula in children with cow's milk protein intolerance/allergy (CMPI/CMPA)].
Minerva Pediatr. 1993 May; 45(5):209-13.MP

Abstract

A study aiming to assess the clinical tolerance of a special follow-up soybean milk formula (Neo-Soyal 2) in children with cow's milk protein intolerance or allergy (CMPI/CMPA) has been conducted in 17 infants and children (9 girls and 8 boys) aged from 6 months to 3 years. All the patients had a past history suggestive of CMPI/CMPA and were fed a restricted hypoallergenic diet with a semi-elemental formula based on protein hydrolysates. At the time of initiation of the study, all the patients were asymptomatic with normal growth while on a semi-elemental diet. The formula with protein hydrolysates was substituted by the test milk (Neo-Soyal 2) and blood samples were taken before and after 2 months. The clinical tolerance to the follow-up soybean formula was considered excellent in 16 children who remained asymptomatic with normal growth velocity. Only one patient developed a severe diarrhoea within 72 hours after introduction of the soybean formula which was stopped. However, after one month he was able to tolerate a certain amount of the soybean milk (240 ml) without symptoms. For all the patients studied, there was no change in the nutritional parameters measured in the blood before and after 2 months of the trial. Likewise, the plasma amino acid levels determined in 2 patients remained unchanged before and after the experimental period. These data indicate that the soybean milk formula used here (Neo-Soyal 2) can be safely given as a substitute of semi-elemental diets during the follow-up of children with CMPI/CMPA after the age of 6 months.

Authors+Show Affiliations

Reparto di Pediatria, Cliniche Universitarie Saint-Luc, Università di Lovanio, Bruxelles, Belgio.No affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Comparative Study
English Abstract
Journal Article

Language

ita

PubMed ID

8366851

Citation

Buts, J P., et al. "[Clinical Evaluation of the Tolerance for a Soy-based Special Milk Formula in Children With Cow's Milk Protein Intolerance/allergy (CMPI/CMPA)]." Minerva Pediatrica, vol. 45, no. 5, 1993, pp. 209-13.
Buts JP, Di Sano C, Hansdorffer S. [Clinical evaluation of the tolerance for a soy-based special milk formula in children with cow's milk protein intolerance/allergy (CMPI/CMPA)]. Minerva Pediatr. 1993;45(5):209-13.
Buts, J. P., Di Sano, C., & Hansdorffer, S. (1993). [Clinical evaluation of the tolerance for a soy-based special milk formula in children with cow's milk protein intolerance/allergy (CMPI/CMPA)]. Minerva Pediatrica, 45(5), 209-13.
Buts JP, Di Sano C, Hansdorffer S. [Clinical Evaluation of the Tolerance for a Soy-based Special Milk Formula in Children With Cow's Milk Protein Intolerance/allergy (CMPI/CMPA)]. Minerva Pediatr. 1993;45(5):209-13. PubMed PMID: 8366851.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Clinical evaluation of the tolerance for a soy-based special milk formula in children with cow's milk protein intolerance/allergy (CMPI/CMPA)]. AU - Buts,J P, AU - Di Sano,C, AU - Hansdorffer,S, PY - 1993/5/1/pubmed PY - 1993/5/1/medline PY - 1993/5/1/entrez SP - 209 EP - 13 JF - Minerva pediatrica JO - Minerva Pediatr. VL - 45 IS - 5 N2 - A study aiming to assess the clinical tolerance of a special follow-up soybean milk formula (Neo-Soyal 2) in children with cow's milk protein intolerance or allergy (CMPI/CMPA) has been conducted in 17 infants and children (9 girls and 8 boys) aged from 6 months to 3 years. All the patients had a past history suggestive of CMPI/CMPA and were fed a restricted hypoallergenic diet with a semi-elemental formula based on protein hydrolysates. At the time of initiation of the study, all the patients were asymptomatic with normal growth while on a semi-elemental diet. The formula with protein hydrolysates was substituted by the test milk (Neo-Soyal 2) and blood samples were taken before and after 2 months. The clinical tolerance to the follow-up soybean formula was considered excellent in 16 children who remained asymptomatic with normal growth velocity. Only one patient developed a severe diarrhoea within 72 hours after introduction of the soybean formula which was stopped. However, after one month he was able to tolerate a certain amount of the soybean milk (240 ml) without symptoms. For all the patients studied, there was no change in the nutritional parameters measured in the blood before and after 2 months of the trial. Likewise, the plasma amino acid levels determined in 2 patients remained unchanged before and after the experimental period. These data indicate that the soybean milk formula used here (Neo-Soyal 2) can be safely given as a substitute of semi-elemental diets during the follow-up of children with CMPI/CMPA after the age of 6 months. SN - 0026-4946 UR - https://www.unboundmedicine.com/medline/citation/8366851/[Clinical_evaluation_of_the_tolerance_for_a_soy_based_special_milk_formula_in_children_with_cow's_milk_protein_intolerance/allergy__CMPI/CMPA_]_ L2 - https://medlineplus.gov/infantandnewbornnutrition.html DB - PRIME DP - Unbound Medicine ER -