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Free erythrocyte porphyrin: hemoglobin ratios, serum ferritin, and transferrin saturation levels during treatment of infants with iron-deficiency anemia.
Blood. 1977 Mar; 49(3):455-62.Blood

Abstract

Free erythrocyte porphyrin:hemoglobin (FEP:Hb) ratios were determined on 20 infants with iron-deficiency anemia. FEB:Hb ratios were compared with simultaneously drawn serum ferritin and serum transferrin saturation levels. FEP:Hb ratios dropped steadily during treatment of the anemic infants, but remained elevated compared to age-matched nonanemic infants, until the anemia was corrected. FEP:Hb ratios detected iron deficiency when acute inflammatory disease was present. Serum ferritin levels and transferrin saturation failed to detect iron deficiency after iron therapy was started or when acute inflammatory disease was present. Measurement of FEP:Hb ratios is a reliable and practical way to make a prompt diagnosis of iron-deficiency anemia in infants.

Links

Publisher Full Text
linkinghub.elsevier.com
linkinghub.elsevier.com

Authors

Thomas WJ
No affiliation info available
Koenig HM
No affiliation info available
Lightsey AL
No affiliation info available
Green R
No affiliation info available

MeSH

Anemia, HypochromicFerritinsFerrous CompoundsHematocritHemoglobinsHumansInfantPorphyrinsTransferrin

Pub Type(s)

Comparative Study
Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

836952

Citation

Thomas, W J., et al. "Free Erythrocyte Porphyrin: Hemoglobin Ratios, Serum Ferritin, and Transferrin Saturation Levels During Treatment of Infants With Iron-deficiency Anemia." Blood, vol. 49, no. 3, 1977, pp. 455-62.
Thomas WJ, Koenig HM, Lightsey AL, et al. Free erythrocyte porphyrin: hemoglobin ratios, serum ferritin, and transferrin saturation levels during treatment of infants with iron-deficiency anemia. Blood. 1977;49(3):455-62.
Thomas, W. J., Koenig, H. M., Lightsey, A. L., & Green, R. (1977). Free erythrocyte porphyrin: hemoglobin ratios, serum ferritin, and transferrin saturation levels during treatment of infants with iron-deficiency anemia. Blood, 49(3), 455-62.
Thomas WJ, et al. Free Erythrocyte Porphyrin: Hemoglobin Ratios, Serum Ferritin, and Transferrin Saturation Levels During Treatment of Infants With Iron-deficiency Anemia. Blood. 1977;49(3):455-62. PubMed PMID: 836952.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Free erythrocyte porphyrin: hemoglobin ratios, serum ferritin, and transferrin saturation levels during treatment of infants with iron-deficiency anemia. AU - Thomas,W J, AU - Koenig,H M, AU - Lightsey,A L,Jr AU - Green,R, PY - 1977/3/1/pubmed PY - 2001/3/28/medline PY - 1977/3/1/entrez SP - 455 EP - 62 JF - Blood JO - Blood VL - 49 IS - 3 N2 - Free erythrocyte porphyrin:hemoglobin (FEP:Hb) ratios were determined on 20 infants with iron-deficiency anemia. FEB:Hb ratios were compared with simultaneously drawn serum ferritin and serum transferrin saturation levels. FEP:Hb ratios dropped steadily during treatment of the anemic infants, but remained elevated compared to age-matched nonanemic infants, until the anemia was corrected. FEP:Hb ratios detected iron deficiency when acute inflammatory disease was present. Serum ferritin levels and transferrin saturation failed to detect iron deficiency after iron therapy was started or when acute inflammatory disease was present. Measurement of FEP:Hb ratios is a reliable and practical way to make a prompt diagnosis of iron-deficiency anemia in infants. SN - 0006-4971 UR - https://www.unboundmedicine.com/medline/citation/836952/Free_erythrocyte_porphyrin:_hemoglobin_ratios_serum_ferritin_and_transferrin_saturation_levels_during_treatment_of_infants_with_iron_deficiency_anemia_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0006-4971(20)70884-0 DB - PRIME DP - Unbound Medicine ER -