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[Correlations of the levels of HbA1c with plasma apoproteins and plasma lipoproteins in type II diabetic patients].
Rev Esp Fisiol 1993; 49(1):23-9RE

Abstract

Plasma apolipoproteins from VLDL, LDL and HDL lipoproteins were measured in 56 male patients with age range 50-60 years and noninsulin-dependent diabetes mellitus (type II) and 81 normal volunteers. Diabetic patients were further divided into two subgroups according to the HbA1c (glycated haemoglobin) concentrations, lower than 7% and higher than 7% respectively, after considering that HbA1c levels may be an appropriate index to monitor long-term blood glucose level. The studied groups, control and diabetic patients, were well matched with regard to age, % of smokers, % drinkers and % hypertensive and physical activity. The relationships between glucose, fructosamine and % HbA1c levels were investigated. In addition, the relationships between glucose, fructosamine, HbA1c levels and apolipoproteins from the lipoproteins were also studied. A significant correlation (p < 0.05) between glucose/fructosamine, glucose/HbA1c and fructosamine/HbA1c was found in both groups of diabetic patients with HbA1c lower than 7% and higher than 7% respectively. However HbA1c levels were positive and significantly (p < 0.05) correlated with the Apo-B and Apo-E and negative but significantly correlated (p < 0.05) with Apo-CII and Apo-CIII from VLDL particle in both groups of diabetic patients.

Authors+Show Affiliations

Laboratorio de Técnicas Instrumentales, Departamento de Nutrición y Bromatología II, Facultad de Farmacia, Madrid, España.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

spa

PubMed ID

8378574

Citation

Ródenas, S, et al. "[Correlations of the Levels of HbA1c With Plasma Apoproteins and Plasma Lipoproteins in Type II Diabetic Patients]." Revista Espanola De Fisiologia, vol. 49, no. 1, 1993, pp. 23-9.
Ródenas S, Sánchez-Cabezudo M, Cuesta C. [Correlations of the levels of HbA1c with plasma apoproteins and plasma lipoproteins in type II diabetic patients]. Rev Esp Fisiol. 1993;49(1):23-9.
Ródenas, S., Sánchez-Cabezudo, M., & Cuesta, C. (1993). [Correlations of the levels of HbA1c with plasma apoproteins and plasma lipoproteins in type II diabetic patients]. Revista Espanola De Fisiologia, 49(1), pp. 23-9.
Ródenas S, Sánchez-Cabezudo M, Cuesta C. [Correlations of the Levels of HbA1c With Plasma Apoproteins and Plasma Lipoproteins in Type II Diabetic Patients]. Rev Esp Fisiol. 1993;49(1):23-9. PubMed PMID: 8378574.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Correlations of the levels of HbA1c with plasma apoproteins and plasma lipoproteins in type II diabetic patients]. AU - Ródenas,S, AU - Sánchez-Cabezudo,M, AU - Cuesta,C, PY - 1993/3/1/pubmed PY - 1993/3/1/medline PY - 1993/3/1/entrez SP - 23 EP - 9 JF - Revista espanola de fisiologia JO - Rev. Esp. Fisiol. VL - 49 IS - 1 N2 - Plasma apolipoproteins from VLDL, LDL and HDL lipoproteins were measured in 56 male patients with age range 50-60 years and noninsulin-dependent diabetes mellitus (type II) and 81 normal volunteers. Diabetic patients were further divided into two subgroups according to the HbA1c (glycated haemoglobin) concentrations, lower than 7% and higher than 7% respectively, after considering that HbA1c levels may be an appropriate index to monitor long-term blood glucose level. The studied groups, control and diabetic patients, were well matched with regard to age, % of smokers, % drinkers and % hypertensive and physical activity. The relationships between glucose, fructosamine and % HbA1c levels were investigated. In addition, the relationships between glucose, fructosamine, HbA1c levels and apolipoproteins from the lipoproteins were also studied. A significant correlation (p < 0.05) between glucose/fructosamine, glucose/HbA1c and fructosamine/HbA1c was found in both groups of diabetic patients with HbA1c lower than 7% and higher than 7% respectively. However HbA1c levels were positive and significantly (p < 0.05) correlated with the Apo-B and Apo-E and negative but significantly correlated (p < 0.05) with Apo-CII and Apo-CIII from VLDL particle in both groups of diabetic patients. SN - 0034-9402 UR - https://www.unboundmedicine.com/medline/citation/8378574/[Correlations_of_the_levels_of_HbA1c_with_plasma_apoproteins_and_plasma_lipoproteins_in_type_II_diabetic_patients]_ L2 - https://medlineplus.gov/a1c.html DB - PRIME DP - Unbound Medicine ER -