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Effect of heparin on hemagglutination by pseudorabies virus.
Am J Vet Res. 1993 Jan; 54(1):99-102.AJ

Abstract

Heparin inhibited hemagglutination (HA) by pseudorabies virus (PRV), but not HA by Akabane virus, bovine adenovirus type 7, Fukuoka virus, Getah virus, Japanese encephalitis virus, and parainfluenza virus type 3 belonging to the families Bunyaviridae, Adenoviridae, Rhabdoviridae, Togaviridae, Flavivi-idae, and Paramyxoviridae, respectively. The minimal inhibitory concentration of heparin required to inhibit 8 HA U of PRV ranged from 0.005 to 0.01 U/ml. Mouse erythrocytes failed to combine with the HA inhibitory factor of heparin. On the other hand, mouse erythrocytes treated with heparinase had greatly reduced agglutinability by PRV. Virus-heparin complex formation could be observed by sedimenting heparin with the virus particles.

Authors+Show Affiliations

Department of Veterinary Epizootiology, College of Agriculture and Veterinary Medicine, Nihon University, Kanagawa, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8381261

Citation

Ohashi, S, et al. "Effect of Heparin On Hemagglutination By Pseudorabies Virus." American Journal of Veterinary Research, vol. 54, no. 1, 1993, pp. 99-102.
Ohashi S, Inaba Y, Kataoka J, et al. Effect of heparin on hemagglutination by pseudorabies virus. Am J Vet Res. 1993;54(1):99-102.
Ohashi, S., Inaba, Y., Kataoka, J., Tetsu, N., Shibata, I., & Asagi, M. (1993). Effect of heparin on hemagglutination by pseudorabies virus. American Journal of Veterinary Research, 54(1), 99-102.
Ohashi S, et al. Effect of Heparin On Hemagglutination By Pseudorabies Virus. Am J Vet Res. 1993;54(1):99-102. PubMed PMID: 8381261.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effect of heparin on hemagglutination by pseudorabies virus. AU - Ohashi,S, AU - Inaba,Y, AU - Kataoka,J, AU - Tetsu,N, AU - Shibata,I, AU - Asagi,M, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez SP - 99 EP - 102 JF - American journal of veterinary research JO - Am. J. Vet. Res. VL - 54 IS - 1 N2 - Heparin inhibited hemagglutination (HA) by pseudorabies virus (PRV), but not HA by Akabane virus, bovine adenovirus type 7, Fukuoka virus, Getah virus, Japanese encephalitis virus, and parainfluenza virus type 3 belonging to the families Bunyaviridae, Adenoviridae, Rhabdoviridae, Togaviridae, Flavivi-idae, and Paramyxoviridae, respectively. The minimal inhibitory concentration of heparin required to inhibit 8 HA U of PRV ranged from 0.005 to 0.01 U/ml. Mouse erythrocytes failed to combine with the HA inhibitory factor of heparin. On the other hand, mouse erythrocytes treated with heparinase had greatly reduced agglutinability by PRV. Virus-heparin complex formation could be observed by sedimenting heparin with the virus particles. SN - 0002-9645 UR - https://www.unboundmedicine.com/medline/citation/8381261/Effect_of_heparin_on_hemagglutination_by_pseudorabies_virus L2 - https://medlineplus.gov/bloodthinners.html DB - PRIME DP - Unbound Medicine ER -