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Amphotericin B therapy in kala-azar.
J Indian Med Assoc. 1993 Apr; 91(4):91-3.JI

Abstract

Twenty-seven adult patients of kala-azar unresponsive to sodium stibogluconate (SSG) were given amphotericin B in the dose schedule of 0.50 mg/kg body weight on alternate days for a total of 21 to 31 infusions, depending upon clinical and parasitological response. A 100% cure rate was achieved at the end of the therapy and no relapse was encountered during 12 months follow-up. Only mild adverse reactions were noted on the day of infusion during therapy. Amphotericin B was found to be an acceptable alternative drug for treatment of such cases.

Authors+Show Affiliations

Giri OP
Department of Medicine, Darbhanga Medical College and Hospital, Laherisarai.

MeSH

AdolescentAdultAmphotericin BDose-Response Relationship, DrugDrug Administration ScheduleFemaleHumansIndiaLeishmaniasis, VisceralMaleRecurrence

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8409490

Citation

Giri, O P.. "Amphotericin B Therapy in Kala-azar." Journal of the Indian Medical Association, vol. 91, no. 4, 1993, pp. 91-3.
Giri OP. Amphotericin B therapy in kala-azar. J Indian Med Assoc. 1993;91(4):91-3.
Giri, O. P. (1993). Amphotericin B therapy in kala-azar. Journal of the Indian Medical Association, 91(4), 91-3.
Giri OP. Amphotericin B Therapy in Kala-azar. J Indian Med Assoc. 1993;91(4):91-3. PubMed PMID: 8409490.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Amphotericin B therapy in kala-azar. A1 - Giri,O P, PY - 1993/4/1/pubmed PY - 1993/4/1/medline PY - 1993/4/1/entrez SP - 91 EP - 3 JF - Journal of the Indian Medical Association JO - J Indian Med Assoc VL - 91 IS - 4 N2 - Twenty-seven adult patients of kala-azar unresponsive to sodium stibogluconate (SSG) were given amphotericin B in the dose schedule of 0.50 mg/kg body weight on alternate days for a total of 21 to 31 infusions, depending upon clinical and parasitological response. A 100% cure rate was achieved at the end of the therapy and no relapse was encountered during 12 months follow-up. Only mild adverse reactions were noted on the day of infusion during therapy. Amphotericin B was found to be an acceptable alternative drug for treatment of such cases. SN - 0019-5847 UR - https://www.unboundmedicine.com/medline/citation/8409490/Amphotericin_B_therapy_in_kala_azar_ DB - PRIME DP - Unbound Medicine ER -