Tags

Type your tag names separated by a space and hit enter

The relationship between stress and symptoms of gastroesophageal reflux: the influence of psychological factors.

Abstract

This paper describes the first controlled study of the relationships among stress, psychological traits associated with chronic anxiety, acid reflux parameters, and perceptions of reflux symptoms. Seventeen subjects with symptomatic reflux disease were studied using a 2 (high vs. low gastrointestinal susceptibility score) x 2 (stress vs. neutral tasks) x 3 (periods 1, 2, or 3) experimental design. It was found that the stress tasks produced significant increases in systolic and diastolic blood pressure, pulse rates, and subjective ratings of anxiety and reflux symptoms. The stress tasks, however, did not influence objective parameters of acid reflux (total acid exposure, number of reflux episodes, duration of longest reflux episode). Moreover, the effect of stress on reflux ratings was due primarily to the responses of the subjects with high gastrointestinal susceptibility scale scores. These subjects' reflux ratings remained at high levels during all stress periods, whereas subjects in all other experimental conditions reported decreased reflux symptoms across periods. These results suggest that reflux patients who are chronically anxious and exposed to prolonged stress may perceive low intensity esophageal stimuli as painful reflux symptoms. Future effort should be devoted to examining the efficacy of anxiolytic and behavioral therapies with these reflux patients.

Authors+Show Affiliations

,

University of Alabama, Birmingham.

, , , , , ,

Source

MeSH

Adaptation, Physiological
Adult
Aged
Anxiety
Blood Pressure
Chronic Disease
Female
Gastroesophageal Reflux
Humans
Hydrogen-Ion Concentration
Male
Middle Aged
Pulse
Stress, Psychological

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, P.H.S.

Language

eng

PubMed ID

8420248

Citation

Bradley, L A., et al. "The Relationship Between Stress and Symptoms of Gastroesophageal Reflux: the Influence of Psychological Factors." The American Journal of Gastroenterology, vol. 88, no. 1, 1993, pp. 11-9.
Bradley LA, Richter JE, Pulliam TJ, et al. The relationship between stress and symptoms of gastroesophageal reflux: the influence of psychological factors. Am J Gastroenterol. 1993;88(1):11-9.
Bradley, L. A., Richter, J. E., Pulliam, T. J., Haile, J. M., Scarinci, I. C., Schan, C. A., ... Salley, A. N. (1993). The relationship between stress and symptoms of gastroesophageal reflux: the influence of psychological factors. The American Journal of Gastroenterology, 88(1), pp. 11-9.
Bradley LA, et al. The Relationship Between Stress and Symptoms of Gastroesophageal Reflux: the Influence of Psychological Factors. Am J Gastroenterol. 1993;88(1):11-9. PubMed PMID: 8420248.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - The relationship between stress and symptoms of gastroesophageal reflux: the influence of psychological factors. AU - Bradley,L A, AU - Richter,J E, AU - Pulliam,T J, AU - Haile,J M, AU - Scarinci,I C, AU - Schan,C A, AU - Dalton,C B, AU - Salley,A N, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez SP - 11 EP - 9 JF - The American journal of gastroenterology JO - Am. J. Gastroenterol. VL - 88 IS - 1 N2 - This paper describes the first controlled study of the relationships among stress, psychological traits associated with chronic anxiety, acid reflux parameters, and perceptions of reflux symptoms. Seventeen subjects with symptomatic reflux disease were studied using a 2 (high vs. low gastrointestinal susceptibility score) x 2 (stress vs. neutral tasks) x 3 (periods 1, 2, or 3) experimental design. It was found that the stress tasks produced significant increases in systolic and diastolic blood pressure, pulse rates, and subjective ratings of anxiety and reflux symptoms. The stress tasks, however, did not influence objective parameters of acid reflux (total acid exposure, number of reflux episodes, duration of longest reflux episode). Moreover, the effect of stress on reflux ratings was due primarily to the responses of the subjects with high gastrointestinal susceptibility scale scores. These subjects' reflux ratings remained at high levels during all stress periods, whereas subjects in all other experimental conditions reported decreased reflux symptoms across periods. These results suggest that reflux patients who are chronically anxious and exposed to prolonged stress may perceive low intensity esophageal stimuli as painful reflux symptoms. Future effort should be devoted to examining the efficacy of anxiolytic and behavioral therapies with these reflux patients. SN - 0002-9270 UR - https://www.unboundmedicine.com/medline/citation/8420248/The_relationship_between_stress_and_symptoms_of_gastroesophageal_reflux:_the_influence_of_psychological_factors_ L2 - https://ClinicalTrials.gov/search/term=8420248 [PUBMED-IDS] DB - PRIME DP - Unbound Medicine ER -