Tags

Type your tag names separated by a space and hit enter

Posterior cranial fossa dimensions in the Chiari I malformation: relation to pathogenesis and clinical presentation.
Neuroradiology. 1993; 35(2):113-8.N

Abstract

Skull dimensions were measured on lateral skull radiographs in 33 adult patients with MRI-verified Chiari I malformations and in 40 controls. The posterior cranial fossa was significantly smaller and shallower in patients than in controls. In the patients, there was a positive correlation between posterior fossa size and the degree of the cerebellar ectopia, which might indicate that a posterior cranial fossa which was originally too small had been expanded by the herniation of hindbrain structures at an early stage. Pyramidal signs and cerebellar symptoms and signs, which may be due to compression of neural structures, were associated with a large degree of ectopia and a relatively large posterior cranial fossa. Syringomyelia and headache, which may be due to the valve action of the herniated cerebellar tissue, were not associated with a particularly large posterior fossa or herniation. No special clinical presentation was associated with a very small posterior cranial fossa, which may indicate that a small posterior cranial fossa per se has little or no clinical significance, although it may be the primary developmental anomaly.

Authors+Show Affiliations

Department of Neurology, Trondheim University Hospital, Norway.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

8433785

Citation

Stovner, L J., et al. "Posterior Cranial Fossa Dimensions in the Chiari I Malformation: Relation to Pathogenesis and Clinical Presentation." Neuroradiology, vol. 35, no. 2, 1993, pp. 113-8.
Stovner LJ, Bergan U, Nilsen G, et al. Posterior cranial fossa dimensions in the Chiari I malformation: relation to pathogenesis and clinical presentation. Neuroradiology. 1993;35(2):113-8.
Stovner, L. J., Bergan, U., Nilsen, G., & Sjaastad, O. (1993). Posterior cranial fossa dimensions in the Chiari I malformation: relation to pathogenesis and clinical presentation. Neuroradiology, 35(2), 113-8.
Stovner LJ, et al. Posterior Cranial Fossa Dimensions in the Chiari I Malformation: Relation to Pathogenesis and Clinical Presentation. Neuroradiology. 1993;35(2):113-8. PubMed PMID: 8433785.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Posterior cranial fossa dimensions in the Chiari I malformation: relation to pathogenesis and clinical presentation. AU - Stovner,L J, AU - Bergan,U, AU - Nilsen,G, AU - Sjaastad,O, PY - 1993/1/1/pubmed PY - 1993/1/1/medline PY - 1993/1/1/entrez SP - 113 EP - 8 JF - Neuroradiology JO - Neuroradiology VL - 35 IS - 2 N2 - Skull dimensions were measured on lateral skull radiographs in 33 adult patients with MRI-verified Chiari I malformations and in 40 controls. The posterior cranial fossa was significantly smaller and shallower in patients than in controls. In the patients, there was a positive correlation between posterior fossa size and the degree of the cerebellar ectopia, which might indicate that a posterior cranial fossa which was originally too small had been expanded by the herniation of hindbrain structures at an early stage. Pyramidal signs and cerebellar symptoms and signs, which may be due to compression of neural structures, were associated with a large degree of ectopia and a relatively large posterior cranial fossa. Syringomyelia and headache, which may be due to the valve action of the herniated cerebellar tissue, were not associated with a particularly large posterior fossa or herniation. No special clinical presentation was associated with a very small posterior cranial fossa, which may indicate that a small posterior cranial fossa per se has little or no clinical significance, although it may be the primary developmental anomaly. SN - 0028-3940 UR - https://www.unboundmedicine.com/medline/citation/8433785/Posterior_cranial_fossa_dimensions_in_the_Chiari_I_malformation:_relation_to_pathogenesis_and_clinical_presentation_ L2 - https://medlineplus.gov/chiarimalformation.html DB - PRIME DP - Unbound Medicine ER -